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Angiozyme

 
National Institutes of Health

Papers overview

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2012
2012
BACKGROUND Serum and plasma levels of vascular endothelial growth factor (VEGF) correlate with prognosis in patients with… Expand
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2005
2005
PURPOSE This study intended to determine the maximum tolerated dose, safety, pharmacokinetic variables, clinical response, and… Expand
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2004
2004
PurposeRPI.4610 (ANGIOZYME) is a chemically stabilized ribozyme targeting vascular endothelial growth factor receptor 1. The… Expand
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Review
2001
Review
2001
Several inhibitors of angiogenesis are being developed for the treatment of cancer. One dominant strategy involves disruption of… Expand
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Review
2000
Review
2000
The discovery of ribozymes by Cech and Altman has fundamentally changed the view of the function of RNA in chemistry, biology… Expand
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2000
2000
The potential acute toxicity of a ribozyme (ANGIOZYME) targeting the flt-1 vascular endothelial growth factor (VEGF) receptor… Expand
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2000
2000
A significant amount of research has been devoted to the chemical stabilization of synthetic ribozymes, in part, so that… Expand
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