FAQ

Angiopoietin-Related Protein 4

Known as: Angiopoietin-Like Protein 4, HFARP, Hepatic Fibrinogen/Angiopoietin-Related Protein 
Angiopoietin-related protein 4 (406 aa, ~45 kDa) is encoded by the human ANGPTL4 gene. This protein plays a role in the modulation of signaling… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2018
05101520042018

Related topics

Related topics

10 relations
ANGPTL4 geneANGPTL4 wt AlleleAngiogenesis PromoterExtracellular Space
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Related mentions per year

Related mentions per year

1940-2018
19401960198020002020
Angiopoietin-Related Protein 4
Signal Transduction
Receptor Signaling
Extracellular Space
Negative Regulation of Apoptosis
PPAR Signaling Pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy.
Animal models link ectopic lipid accumulation to renal dysfunction, but whether this process occurs in the human kidney is… (More)
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2013
2013
Angiopoietin-like protein 4 inhibition of lipoprotein lipase: evidence for reversible complex formation.
Elevated triglycerides are associated with an increased risk of cardiovascular disease, and lipoprotein lipase (LPL) is the rate… (More)
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2012
2012
Protection against myocardial infarction and no-reflow through preservation of vascular integrity by angiopoietin-like 4.
BACKGROUND Increased permeability, predominantly controlled by endothelial junction stability, is an early event in the… (More)
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Highly Cited
2009
Highly Cited
2009
Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator–Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans
OBJECTIVE Long-chain fatty acids (LCFAs) contribute to metabolic homeostasis in part via gene regulation. This study's objective… (More)
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Highly Cited
2009
Highly Cited
2009
Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids.
OBJECTIVE Plasma lipoprotein levels are determined by the balance between lipoprotein production and clearance. Recently… (More)
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2008
2008
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.
The development of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands for the treatment of diseases… (More)
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Highly Cited
2007
Highly Cited
2007
Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes
The effect of hypoxia, induced by incubation under low (1%) oxygen tension or by exposure to CoCl2, on the expression and… (More)
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Highly Cited
2006
Highly Cited
2006
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity.
Proteins secreted from adipose tissue are increasingly recognized to play an important role in the regulation of glucose… (More)
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Highly Cited
2004
Highly Cited
2004
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate…
The fasting-induced adipose factor (FIAF, ANGPTL4, PGAR, HFARP) was previously identified as a novel adipocytokine that was up… (More)
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2004
2004
Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4.
Angiopoietin-like protein 4 (Angptl4) is a recently identified circulating protein expressed primarily in adipose tissue and… (More)
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