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Angiopoietin-Related Protein 4

Known as: Angiopoietin-Like Protein 4, HFARP, Hepatic Fibrinogen/Angiopoietin-Related Protein 
Angiopoietin-related protein 4 (406 aa, ~45 kDa) is encoded by the human ANGPTL4 gene. This protein plays a role in the modulation of signaling… 
National Institutes of Health

Related topics

Related topics

10 relations
ANGPTL4 geneANGPTL4 wt AlleleAngiogenesis PromoterExtracellular Space

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy
Animal models link ectopic lipid accumulation to renal dysfunction, but whether this process occurs in the human kidney is… 
Highly Cited
2011
Highly Cited
2011
Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity
Background— Adipose tissue expands in response to excess caloric intake, but individuals prone to deposit visceral instead of… 
Highly Cited
2011
Highly Cited
2011
Hypoxia‐inducible factor 1 alpha–activated angiopoietin‐like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule‐1/integrin β1 signaling in human hepatocellular carcinoma
Angiopoietin‐like protein 4 (ANGPTL4) plays complex and often contradictory roles in vascular biology and tumor metastasis, but… 
Highly Cited
2010
Highly Cited
2010
Absence of intestinal microbiota does not protect mice from diet-induced obesity
The gut microbiota has been implicated in host nutrient absorption and energy homeostasis. We studied the influence of different… 
Highly Cited
2007
Highly Cited
2007
Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes
The effect of hypoxia, induced by incubation under low (1%) oxygen tension or by exposure to CoCl2, on the expression and… 
Highly Cited
2007
Highly Cited
2007
Angptl4 Upregulates Cholesterol Synthesis in Liver via Inhibition of LPL- and HL-Dependent Hepatic Cholesterol Uptake
Background—Dysregulation of plasma lipoprotein levels may increase the risk for atherosclerosis. Recently, angiopoietin-like… 
Highly Cited
2006
Highly Cited
2006
The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity*
Proteins secreted from adipose tissue are increasingly recognized to play an important role in the regulation of glucose… 
Highly Cited
2004
Highly Cited
2004
Oligomerization and Regulated Proteolytic Processing of Angiopoietin-like Protein 4*
Angiopoietin-like protein 4 (Angptl4) is a recently identified circulating protein expressed primarily in adipose tissue and… 
Highly Cited
2004
Highly Cited
2004
The Direct Peroxisome Proliferator-activated Receptor Target Fasting-induced Adipose Factor (FIAF/PGAR/ANGPTL4) Is Present in Blood Plasma as a Truncated Protein That Is Increased by Fenofibrate…
The fasting-induced adipose factor (FIAF, ANGPTL4, PGAR, HFARP) was previously identified as a novel adipocytokine that was up… 
Highly Cited
2002
Highly Cited
2002
Identification of silencing of nine genes in human gastric cancers.
Aberrant methylations in human gastric cancers were searched for by a genome scanning technique, methylation-sensitive… 
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