Anaphylatoxins

Known as: Anaphylatoxins [Chemical/Ingredient] 
Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
The anaphylatoxin (AT) C3a, C5a and C5a-desArg are generally considered pro-inflammatory polypeptides generated after proteolytic… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BACKGROUND There is an urgent need to determine whether oversulfated chondroitin sulfate (OSCS), a compound contaminating heparin… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Costimulatory signals are critical to T cell activation, but how their effects are mediated remains incompletely characterized… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Complement-derived anaphylatoxins regulate immune and inflammatory responses through G-protein-coupled receptor (GPCR)-mediated… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Review
2004
Review
2004
The complement (C) inflammatory cascade is part of the phylogenetically ancient innate immune response and is crucial to our… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
C3a and C5a anaphylatoxins are cytokine-like polypeptides generated during complement (C) system activation and released at the… (More)
Is this relevant?
Review
2003
Review
2003
This article critically examines and evaluates the likely mechanisms that contribute to prolonged circulation times of sterically… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
1986
Review
1986
Anaphylatoxins, in particular C3a and C5a, have various biological activities which suggest a role as mediators of inflammatory… (More)
Is this relevant?
Review
1984
Review
1984
Chemical and physical characterization of the anaphylatoxin molecules have provided a reasonably clear description of the… (More)
Is this relevant?
Highly Cited
1981
Highly Cited
1981
We observed complement activation in 15 adults undergoing total cardiopulmonary bypass. Plasma levels of C3a were significantly… (More)
Is this relevant?