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Amuvatinib Hydrochloride

Known as: 1-Piperazinecarbothioamide, N-(1,3-Benzodioxol-5-Ylmethyl)-4-Benzofuro(3,2-D)Pyrimidin-4-Yl-, Hydrochloride (1:1), N-(1,3-Benzodioxol-5-Ylmethyl)-4-(Benzofuro(3,2-D)Pyrimidin-4-Yl)Piperazine-1- Carbothioamide Monohydrochloride 
The hydrochloride salt of an orally bioavailable synthetic carbothioamide with potential antineoplastic activity. Multitargeted receptor tyrosine… 
National Institutes of Health

Related topics

Related topics

4 relations
MP-470 HCIMP470Receptor Tyrosine Kinase Inhibitionamuvatinib

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Synthesis of Heterocyclic Thioamides and Copper(II) Coordination Compounds Based on Them
Arylamides of hetaryl-2-thiocarboxylic acid were synthesized via Willgerodt–Kindler modified reaction. The final products were… 
2016
2016
Synthesis, spectral studies, in vitro and molecular docking studies of novel hydrazinyl carbothioamide derivatives
2014
2014
Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides
A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure… 
2012
2012
Safety, tolerability, and pharmacokinetics of amuvatinib from three phase 1 clinical studies in healthy volunteers
PurposeAmuvatinib is a multi-targeted tyrosine kinase inhibitor with activity that also disrupts DNA damage repair through… 
2012
2012
Synthesized Pyrazoline-Carbothioamide as Potent Antitubercular Agent
2003
2003
MCC-134, a Single Pharmacophore, Opens Surface ATP–Sensitive Potassium Channels, Blocks Mitochondrial ATP–Sensitive Potassium Channels, and Suppresses Preconditioning
Background— MCC-134 (1-[4-(H-imidazol-1-yl)benzoyl]-N-methylcyclobutane-carbothioamide), a newly developed analog of aprikalim… 
1990
1990
N-(4-hydroxy-3-methoxybenzylidene)hydrazine carbothioamide as a selective and sensitive reagent for the rapid spectrophotometric determination of osmium(VI)
N-​(4-​Hydroxy-​3-​methoxybenzylidene)​hydrazine carbothioamide is proposed as a selective and sensitive reagent for the rapid… 
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