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Ampligen
National Institutes of Health
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Broader (1)
Rintatolimod
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
A clinical grade poly I:C-analogue (Ampligen) promotes optimal DC maturation and Th1-type T cell responses of healthy donors and cancer patients in vitro.
H. Navabi
,
B. Jasani
,
+5 authors
M. Adams
Vaccine
2009
Corpus ID: 205577320
Maturation of dendritic cells (DC) can be triggered in vitro by inflammatory cytokines or Toll-like receptor (TLR) ligands such…
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Highly Cited
2009
Highly Cited
2009
A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo
C. Day
,
R. Baric
,
+5 authors
D. Barnard
Virology
2009
Corpus ID: 1434364
Abstract Severe acute respiratory syndrome (SARS) is a highly lethal emerging disease caused by coronavirus SARS-CoV. New…
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Highly Cited
2006
Highly Cited
2006
Evaluation of Immunomodulators, Interferons and Known in Vitro SARS-CoV Inhibitors for Inhibition of SARS-Cov Replication in BALB/c Mice
D. Barnard
,
C. Day
,
+5 authors
R. Sidwell
Antiviral chemistry & chemotherapy
2006
Corpus ID: 3475647
Compounds approved for therapeutic use and in vitro inhibitors of severe acute respiratory syndrome coronavirus (SARS-CoV) were…
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Highly Cited
2004
Highly Cited
2004
Effect of Interferon-Alpha and Interferon-Inducers on West Nile Virus in Mouse and Hamster Animal Models
J. Morrey
,
C. Day
,
J. Julander
,
L. Blatt
,
D. Smee
,
R. Sidwell
Antiviral chemistry & chemotherapy
2004
Corpus ID: 21723623
The recent West Nile virus (WNV) outbreak in the United States has increased the need to identify effective therapies. Studies…
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Highly Cited
2004
Highly Cited
2004
The Interferon Inducer Ampligen [Poly(I)-Poly(C12U)] Markedly Protects Mice against Coxsackie B3 Virus-Induced Myocarditis
E. Padalko
,
D. Nuyens
,
+5 authors
J. Neyts
Antimicrobial Agents and Chemotherapy
2004
Corpus ID: 22619876
ABSTRACT Viral replication, as well as an immunopathological component, is assumed to be involved in coxsackie B virus-induced…
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Review
2003
Review
2003
Dendritic cell (DC) based therapy for cervical cancer: use of DC pulsed with tumour lysate and matured with a novel synthetic clinically non-toxic double stranded RNA analogue poly [I]:poly [C(12)U…
M. Adams
,
H. Navabi
,
+5 authors
M. Mason
Vaccine
2003
Corpus ID: 40285986
Human papilloma virus (HPV) found in 99.7% of cervical cancers represents an attractive immunotherapeutic target for novel…
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Highly Cited
2003
Highly Cited
2003
Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice
P. Leyssen
,
C. Drosten
,
+4 authors
J. Neyts
Antimicrobial Agents and Chemotherapy
2003
Corpus ID: 18376890
ABSTRACT We evaluated the prophylactic and therapeutic efficacy of interferon α-2b, pegylated interferon α-2b, poly(I · C), and…
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1991
1991
Mismatched double-stranded RNA, Ampligen (poly(I): poly(C12U), demonstrates antiviral and immunostimulatory activities in HIV disease.
W. A. Carter
,
D. Ventura
,
D. Shapiro
,
D. Strayer
,
D. Gillespie
,
H. Hubbell
International journal of immunopharmacology
1991
Corpus ID: 25469840
Mismatched double-stranded RNA (Ampligen) has broad spectrum antiviral and immunomodulatory activities. These activities generate…
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Highly Cited
1987
Highly Cited
1987
CLINICAL, IMMUNOLOGICAL, AND VIROLOGICAL EFFECTS OF AMPLIGEN, A MISMATCHED DOUBLE-STRANDED RNA, IN PATIENTS WITH AIDS OR AIDS-RELATED COMPLEX
WilliamA. Carter
,
I. Brodsky
,
M. Pellegrino
,
H. Henriques
,
D. Gillespie
The Lancet
1987
Corpus ID: 38926127
10 patients with the acquired immunodeficiency syndrome (AIDS), AIDS-related complex (ARC), or lymphadenopathy syndrome (LAS…
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1987
1987
MISMATCHED DOUBLE-STRANDED RNA (AMPLIGEN) REDUCES CONCENTRATION OF ZIDOVUDINE (AZIDOTHYMIDINE) REQUIRED FOR IN-VITRO INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS
W. Mitchell
,
D. Montefiori
,
W. E. Robinson
,
DavidR. Strayer
,
WilliamA. Carter
The Lancet
1987
Corpus ID: 40924862
'Ampligen', a non-toxic, mismatched polymer of double-stranded RNA with antiviral and immunomodulatory activities reduced the…
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