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Ampligen

National Institutes of Health

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Rintatolimod

Papers overview

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2011
2011
Rapid, non-invasive imaging of alphaviral brain infection: reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals.
Highly Cited
2009
Highly Cited
2009
PolyI:polyC12U adjuvant-combined intranasal vaccine protects mice against highly pathogenic H5N1 influenza virus variants.
2007
2007
Correlation between breakdown of the blood-brain barrier and disease outcome of viral encephalitis in mice.
Highly Cited
2003
Highly Cited
2003
Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice
ABSTRACT We evaluated the prophylactic and therapeutic efficacy of interferon α-2b, pegylated interferon α-2b, poly(I · C), and… 
Review
2003
Review
2003
Dendritic cell (DC) based therapy for cervical cancer: use of DC pulsed with tumour lysate and matured with a novel synthetic clinically non-toxic double stranded RNA analogue poly [I]:poly [C(12)U…
1995
1995
Long Term Improvements in Patients with Chronic Fatigue Syndrome Treated with Ampligen
Fifteen patients who fit the CDC definition of chronic fatigue syndrome (CFS) and had evidence of severe reduction in performance… 
1991
1991
Varying role of alpha/beta interferon in the antiviral efficacy of synthetic immunomodulators against Semliki Forest virus infection.
1989
1989
In vitro evaluation of mismatched double-stranded RNA (ampligen) for combination therapy in the treatment of acquired immunodeficiency syndrome.
Multiple drug effect analyses with mismatched double-stranded RNA (mismatched dsRNA or Ampligen) as a core drug were performed to… 
1988
1988
Comparative study of various immunomodulators for macrophage and natural killer cell activation and antiviral efficacy against exotic RNA viruses.
1985
1985
Preclinical studies with Ampligen (mismatched double-stranded RNA).
Historically, double-stranded (ds) RNAs have been largely over-looked as potentially valuable anticancer/antiviral drugs… 
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