Amorolfine

Known as: Amorolfin 
A morpholine antifungal agent for topical use. Amorolfine inhibits delta-14-reductase and delta-7,8-isomerase, which depletes ergosterol and causes… (More)
National Institutes of Health

Papers overview

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2009
2009
BACKGROUND Standard treatment for onychomycosis often results in less than half of subjects achieving disease-free nails… (More)
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Review
2008
Review
2008
Treatment of dermatophyte infection involves primarily oral and/or topical formulations of azoles or allylamines, particularly… (More)
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Highly Cited
2003
Highly Cited
2003
The azole antifungal fluconazole possesses only fungistatic activity in Candida albicans and, therefore, this human pathogen is… (More)
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2002
2002
The therapeutic efficacy of KP-103, a novel topical triazole, in a guinea pig tinea unguium model was investigated. Experimental… (More)
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2001
2001
  • M. Lecha
  • The British journal of dermatology
  • 2001
OBJECTIVE In an open, randomized, clinical study of toenail onychomycosis with matrix area involvement, two alternative regimens… (More)
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Highly Cited
1997
Highly Cited
1997
Resistance to azole antifungal agents in Candida albicans can be mediated by multidrug efflux transporters. In a previous study… (More)
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Highly Cited
1996
Highly Cited
1996
Some Candida albicans isolates from AIDS patients with oropharyngeal candidiasis are becoming resistant to the azole antifungal… (More)
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1993
1993
Amorolfine penetrates rapidly into the nail after topical application. The kinetics of penetration follow an exponential law as… (More)
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1992
1992
Amorolfine is a new topical antifungal of the phenylpropyl morpholine class which is highly active both in vitro and in vivo… (More)
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1992
1992
Altogether 157 patients with onychomycosis affecting not more than 80% of the surface area of nail with intact lunula and matrix… (More)
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