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Amorolfine

Known as: Amorolfin 
A morpholine antifungal agent for topical use. Amorolfine inhibits delta-14-reductase and delta-7,8-isomerase, which depletes ergosterol and causes… 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

Amorolfine hydrochlorideOdenil

Broader (2)

Antifungal AgentsMorpholines

Papers overview

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2016
2016
Combination therapy for onychomycosis using a fractional 2940-nm Er:YAG laser and 5 % amorolfine lacquer
Onychomycosis remains difficult to cure by traditional methods. The aim of this study was to evaluate the efficacy of combination… 
2015
2015
Antifungal therapy for onychomycosis in children.
2015
2015
Silicon Incorporated Morpholine Antifungals: Design, Synthesis, and Biological Evaluation.
Known morpholine class antifungals (fenpropimorph, fenpropidin, and amorolfine) were synthetically modified through silicon… 
2005
2005
Candida-related denture stomatitis: a pilot study of the efficacy of an amorolfine antifungal varnish.
PURPOSE Candida albicans is a component of the normal oral microflora, but local and systemic factors can transform this… 
Highly Cited
2001
Highly Cited
2001
MDR1-Mediated Drug Resistance inCandida dubliniensis
ABSTRACT Candida dubliniensis is a recently described opportunistic fungal pathogen that is closely related to Candida albicans… 
Review
1999
Review
1999
Management of Onychomycoses
Onychomycoses, infections of the nail caused by fungi, are amongst the most common illnesses. Because of the high incidence of… 
Review
1995
Review
1995
Therapeutic strategies in onychomycosis
Highly Cited
1992
Highly Cited
1992
Topical treatment of onychomycosis with amorolfine 5% nail lacquer: comparative efficacy and tolerability of once and twice weekly use.
456 patients with onychomycosis were treated once or twice weekly for up to 6 months with amorolfine 5% nail lacquer in an open… 
1992
1992
Determination of the subungual antifungal activity of amorolfine after 1 month's treatment in patients with onychomycosis: comparison of two nail lacquer formulations
Onychomycosis is common worldwide, about 10% of all dermatomycosis being fungal infections of the nails.1 Up until now no… 
1991
1991
A randomized comparative study: Amorolfine (cream 0.125%, 0.25% and 0.5%) in dermatomy coses
In a double-blind randomized comparative study, 75 patients with dermatomycoses (one cutaneous candidosis and 74 dermatophyte… 
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