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Amodiaquine

Known as: Amodiachin, Amodiaquina, Amodiaquin 
An orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. Similar in structure and activity to chloroquine… 
National Institutes of Health

Related topics

Related topics

17 relations

Narrower (9)

2',6'-difluoroamodiaquine4'-dehydroxy-4'-fluoroamodiaquineAmodiaquine hydrochlorideCamoquine

Broader (1)

Antimalarials
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya
Objectives  Many countries are now adopting artemisinin‐based combination therapy (ACT) for treatment of Plasmodium falciparum… 
Highly Cited
2005
Highly Cited
2005
The quality of sulphadoxine‐pyrimethamine and amodiaquine products in the Kenyan retail sector
Background and objective:  Malaria is a disease of major public health importance in Kenya killing 26 000 children under 5 years… 
2005
2005
Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine–pyrimethamine for treatment of uncomplicated Plasmodium…
Introduction  In South and Central Asia resistance to chloroquine (CQ) has reached unmanageable levels, and resistance to… 
Highly Cited
2004
Highly Cited
2004
Animal models of idiosyncratic drug reactions.
Highly Cited
2003
Highly Cited
2003
Efficacy of amodiaquine alone and combined with sulfadoxine-pyrimethamine and of sulfadoxine pyrimethamine combined with artesunate.
The safety and the efficacy of amodiaquine (AQ) alone, AQ plus sulfadoxine-pyrimethamine (SP) (AQ plus SP), and artesunate (ART… 
Highly Cited
2000
Highly Cited
2000
Effect of three structurally related antimalarial drugs on liver microsomal components and lipid peroxidation in rats.
1997
1997
Efficacy of certain quinolines as pharmacological antagonists in botulinum neurotoxin poisoning.
1991
1991
Pyronaridine: A new antimalarial drug.
Highly Cited
1986
Highly Cited
1986
In Vitro Amoebicidal Testing of Natural Products; Part I. Methodology
in vitro Entamoeba histolytica Cinchona Brucea in vitro 
Highly Cited
1973
Highly Cited
1973
Amodiaquine-induced Agranulocytosis: Toxic Effect of Amodiaquine in Bone Marrow Cultures In Vitro
A case of agranulocytosis is reported in which amodiaquine, to which the patient had been exposed, was found to be toxic to the… 
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