Amodiaquine

Known as: Amodiachin, Amodiaquina, Amodiaquin 
An orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. Similar in structure and activity to chloroquine… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Combination antimalarial therapy is advocated to improve treatment efficacy and limit selection of drug-resistant… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Artemisinin-based combination regimens are widely advocated for malarial treatment, but other effective regimens might… (More)
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Highly Cited
2007
Highly Cited
2007
The artemisinin-based combination therapies artemether-lumefantrine (AL) and amodiaquine (AQ) plus artesunate have been adopted… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Many countries in Africa are considering a change to combination treatment for falciparum malaria because of the… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND This is the first clinical trial comparing the efficacy of artesunate plus amodiaquine (ASAQ) and artemether… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND New antimalarial treatments are urgently needed in sub-Saharan Africa. Improved therapies should decrease failure… (More)
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Highly Cited
2002
Highly Cited
2002
Amodiaquine (AQ) metabolism to N-desethylamodiaquine (DEAQ) is the principal route of disposition in humans. Using human liver… (More)
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Highly Cited
2002
Highly Cited
2002
Plasmodium falciparum chloroquine resistance is a major cause of worldwide increases in malaria mortality and morbidity. Recent… (More)
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Review
1996
Review
1996
Malaria is associated with a reduction in the systemic clearance and apparent volume of distribution of the cinchona alkaloids… (More)
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Highly Cited
1986
Highly Cited
1986
Seven cases of agranulocytosis and two of liver damage that were probably due to amodiaquine treatment were studied. In five… (More)
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