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Amlodipine

Known as: 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, Amlodipine [Chemical/Ingredient], Amlodipino 
A synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend… Expand
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Highly Cited
2006
Highly Cited
2006
Under the heading ‘Hypertension, diabetes, and other disorders’ on page 1358, the guidelines1 lean on the taskforce report on CVD… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The apparent shortfall in prevention of coronary heart disease (CHD) noted in early hypertension trials has been… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial was designed to test the hypothesis that for the… Expand
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Highly Cited
2002
Highly Cited
2002
CONTEXT Antihypertensive therapy is well established to reduce hypertension-related morbidity and mortality, but the optimal… Expand
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Highly Cited
2002
Highly Cited
2002
Context. Blood pressure control (<140/90 mm Hg) rates for hypertension fall far short of the US national goal of 50% or more… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND It is unknown whether either the angiotensin-II-receptor blocker irbesartan or the calcium-channel blocker amlodipine… Expand
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Highly Cited
2001
Highly Cited
2001
CONTEXT Incidence of end-stage renal disease due to hypertension has increased in recent decades, but the optimal strategy for… Expand
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE ACE inhibitors and calcium antagonists may favorably affect serum lipids and glucose metabolism. The primary aim of the… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Previous studies have shown that calcium-channel blockers increase morbidity and mortality in patients with chronic… Expand
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