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Amlodipine

Known as: 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, Amlodipine [Chemical/Ingredient], Amlodipino 
A synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend… 
Highly Cited
2006
Highly Cited
2006
Under the heading ‘Hypertension, diabetes, and other disorders’ on page 1358, the guidelines1 lean on the taskforce report on CVD… 
Highly Cited
2006
Highly Cited
2006
Background— Different blood pressure (BP)–lowering drugs could have different effects on central aortic pressures and thus… 
Highly Cited
2002
Highly Cited
2002
CONTEXT Antihypertensive therapy is well established to reduce hypertension-related morbidity and mortality, but the optimal… 
Highly Cited
2001
Highly Cited
2001
BACKGROUND It is unknown whether either the angiotensin-II-receptor blocker irbesartan or the calcium-channel blocker amlodipine… 
Highly Cited
2001
Highly Cited
2001
CONTEXT Incidence of end-stage renal disease due to hypertension has increased in recent decades, but the optimal strategy for… 
Highly Cited
2000
Highly Cited
2000
BackgroundThe results of angiographic studies have suggested that calcium channel–blocking agents may prevent new coronary lesion… 
Highly Cited
1996
Highly Cited
1996
BACKGROUND Previous studies have shown that calcium-channel blockers increase morbidity and mortality in patients with chronic…