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The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend… Expand BACKGROUND
The apparent shortfall in prevention of coronary heart disease (CHD) noted in early hypertension trials has been… Expand BACKGROUND
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial was designed to test the hypothesis that for the… Expand CONTEXT
Antihypertensive therapy is well established to reduce hypertension-related morbidity and mortality, but the optimal… Expand Context. Blood pressure control (<140/90 mm Hg) rates for hypertension fall far short of the US national goal of 50% or more… Expand BACKGROUND
It is unknown whether either the angiotensin-II-receptor blocker irbesartan or the calcium-channel blocker amlodipine… Expand CONTEXT
Incidence of end-stage renal disease due to hypertension has increased in recent decades, but the optimal strategy for… Expand OBJECTIVE ACE inhibitors and calcium antagonists may favorably affect serum lipids and glucose metabolism. The primary aim of the… Expand BACKGROUND
Previous studies have shown that calcium-channel blockers increase morbidity and mortality in patients with chronic… Expand