FAQ

Amlodipine Maleate

Known as: Amlodipine Maleate (1:1) 
The maleate salt of amlodipine, a synthetic phenylpyridine vasodilator with antihypertensive and antianginal effects. Amlodipine inhibits the influx… (More)
National Institutes of Health

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Topic mentions per year

1991-2012
01219912012

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Amlodipine

Related mentions per year

Related mentions per year

1985-2018
19801990200020102020
Amlodipine Maleate
Amlodipine

Papers overview

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2010
2010
Separation, Identification and Structural Elucidation of a New Impurity in the Drug Substance of Amlodipine Maleate Using LC-MS/MS, NMR and IR
Amlodipine maleate is a maleate salt of 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2chlorophenyl)-6-methyl-1,4-dihydropyridine… (More)
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2009
2009
Liquid chromatography-mass spectrometry method for the determination of amlodipine in human plasma and its application in a bioequivalence study.
A sensitive and selective liquid chromatographic-mass spectrometric (LC-MS) method for the determination of amlodipine (CAS 88150… (More)
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2008
2008
Application of liquid chromatography-two-dimensional nuclear magnetic resonance spectroscopy using pre-concentration column trapping and liquid chromatography-mass spectrometry for the identification…
Application of the HPLC hyphenated techniques of LC-two-dimensional (2D) NMR using pre-concentration column trapping and LC-MS… (More)
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2007
2007
Single-dose, randomized, crossover bioequivalence study of amlodipine maleate versus amlodipine besylate in healthy volunteers.
Amlodipine, marketed primarily as a besylate salt, is a calcium channel blocker used for treating essential hypertension… (More)
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2006
2006
Identification and characterization of potential impurities of amlodipine maleate.
Six impurities ranging from 0.43 to 1.42% in amlodipine maleate were detected by a simple isocratic reverse-phase high… (More)
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2005
2005
Results of a multicenter, 8-week, parallel-group, randomized,double-blind, double-dummy, Phase III clinical trial to evaluate the efficacy and tolerability of amlodipine maleate versus amlodipine…
BACKGROUND Recently, amlodipine maleate was developed and tested in preclinical and Phase I clinical trials in Korea. The studies… (More)
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1997
1997
Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)
Problems with sexual function have been a long-standing concern in the treatment of hypertension and may influence the choice of… (More)
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1997
1997
Relationships of quality-of-life measures to long-term lifestyle and drug treatment in the Treatment of Mild Hypertension Study.
OBJECTIVES To compare 5 antihypertensive drugs and placebo for changes in quality of life (QL). To assess the relationship of… (More)
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Highly Cited
1995
Highly Cited
1995
Comparison of five antihypertensive monotherapies and placebo for change in left ventricular mass in patients receiving nutritional-hygienic therapy in the Treatment of Mild Hypertension Study (TOMHS…
BACKGROUND Increased left ventricular mass (LVM) by echocardiography is associated with increased risk of cardiovascular disease… (More)
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Highly Cited
1993
Highly Cited
1993
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
OBJECTIVE To compare six antihypertensive interventions for the treatment of mild hypertension. DESIGN Randomized, double-blind… (More)
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