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Amlodipine Maleate

Known as: Amlodipine Maleate (1:1) 
The maleate salt of amlodipine, a synthetic phenylpyridine vasodilator with antihypertensive and antianginal effects. Amlodipine inhibits the influx… 
National Institutes of Health

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Amlodipine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Potential concerns about generic substitution: bioequivalence versus therapeutic equivalence of different amlodipine salt forms
  • P. Meredith
  • Current Medical Research and Opinion
  • 2009
  • Corpus ID: 24582659
ABSTRACT Background and scope: Whether generic drug products are truly therapeutically identical and interchangeable with their… 
2009
2009
Liquid chromatography-mass spectrometry method for the determination of amlodipine in human plasma and its application in a bioequivalence study.
A sensitive and selective liquid chromatographic-mass spectrometric (LC-MS) method for the determination of amlodipine (CAS 88150… 
2007
2007
Single-Dose, Randomized, Crossover Bioequivalence Study of Amlodipine Maleate versus Amlodipine Besylate in Healthy Volunteers
Amlodipine, marketed primarily as a besylate salt, is a calcium channel blocker used for treating essential hypertension… 
Highly Cited
1997
Highly Cited
1997
Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)
Problems with sexual function have been a long-standing concern in the treatment of hypertension and may influence the choice of… 
Highly Cited
1997
Highly Cited
1997
Relationships of quality-of-life measures to long-term lifestyle and drug treatment in the Treatment of Mild Hypertension Study.
OBJECTIVES To compare 5 antihypertensive drugs and placebo for changes in quality of life (QL). To assess the relationship of… 
Highly Cited
1995
Highly Cited
1995
Comparison of five antihypertensive monotherapies and placebo for change in left ventricular mass in patients receiving nutritional-hygienic therapy in the Treatment of Mild Hypertension Study (TOMHS…
BACKGROUND Increased left ventricular mass (LVM) by echocardiography is associated with increased risk of cardiovascular disease… 
Highly Cited
1993
Highly Cited
1993
Treatment of Mild Hypertension Study: Final Results
Objective. —To compare six antihypertensive interventions for the treatment of mild hypertension. Design. —Randomized, double… 
Highly Cited
1993
Highly Cited
1993
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
OBJECTIVE To compare six antihypertensive interventions for the treatment of mild hypertension. DESIGN Randomized, double-blind… 
Highly Cited
1993
Highly Cited
1993
The treatment of mild hypertension study.
To the Editor. —The Treatment of Mild Hypertension Study (TOMHS) 1 represents a worthy contribution to the evaluation of… 
1991
1991
The treatment of mild hypertension study. A randomized, placebo-controlled trial of a nutritional-hygienic regimen along with various drug monotherapies. The Treatment of Mild Hypertension Research…
  • Archives of Internal Medicine
  • 1991
  • Corpus ID: 24441350
There is no consensus for the optimal treatment program for individuals with mild hypertension, including whether treatment… 
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