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Aminoglycoside-induced hearing loss

Known as: Hearing loss, aminoglycoside-induced 
Partial or complete loss of hearing following ingestion of aminoglycoside antibiotics. [HPO:probinson, pmid:2669624]
National Institutes of Health

Related topics

Related topics

1 relation
DEAFNESS, AMINOGLYCOSIDE-INDUCED

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Increased risk of aminoglycoside-induced hearing loss in MDR-TB patients with HIV coinfection.
SETTING A high proportion of individuals with multidrug-resistant tuberculosis (MDR-TB) develop permanent hearing loss due to… 
Review
2016
Review
2016
PharmGKB summary: very important pharmacogene information for MT-RNR1
Departments of Genetics, Bioengineering, Stanford University, Stanford, California and Department of Pediatrics, Division of… 
Highly Cited
2015
Highly Cited
2015
Endotoxemia-mediated inflammation potentiates aminoglycoside-induced ototoxicity
Endotoxemia-mediated inflammation potentiates cochlear uptake of aminoglycosides and subsequent cochleotoxicity. Inflammation… 
Highly Cited
2010
Highly Cited
2010
Mitochondrial haplotypes may modulate the phenotypic manifestation of the deafness-associated 12S rRNA 1555A>G mutation.
Review
2007
Review
2007
Aspirin attenuates gentamicin ototoxicity: From the laboratory to the clinic
Review
2007
Review
2007
Pharmacogenomic testing to prevent aminoglycoside-induced hearing loss in cystic fibrosis patients: potential impact on clinical, patient, and economic outcomes
Background: Aminoglycosides are commonly used in cystic fibrosis patients to treat Pseudomonas aeruginosa respiratory infections… 
2006
2006
Hearing loss in patients with vestibulotoxic reactions to gentamicin therapy.
OBJECTIVES To determine whether patients with vestibulotoxic reactions to gentamicin have hearing thresholds worse than predicted… 
2005
2005
Genetic features, clinical phenotypes, and prevalence of sensorineural hearing loss associated with the 961delT mitochondrial mutation.
1998
1998
Are aminoglycoside antibiotics excitotoxic?
GUINEA pigs received gentamicin to induce a profound hearing loss (61 dB auditory threshold shift at 18kHz). Concomitant… 
Review
1997
Review
1997
Prevention of aminoglycoside-induced hearing loss.
This review discusses the current problem of ototoxicity associated with the worldwide use of aminoglycoside antibiotics… 
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