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Amikacin

Known as: O-3-amino-3-Deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine, Amikacina, Amicacin 
A broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the… 
National Institutes of Health

Related topics

Related topics

29 relations

Narrower (7)

3',4'-dideoxyamikacin3'-deoxyamikacinAmikacina NormonAmikin
Amikacin SulfateAmikacin:Susc:Pt:Isolate:OrdQn:Agar diffusionAminoglycosidesBacterial Infections

Broader (1)

Anti-Bacterial Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1992
1992
Intracardiac thrombus formation with rapidly progressive heart failure in the neonate: treatment with tissue type plasminogen activator.
A newborn is described in whom the use of a central venous line was complicated by septicaemia and by intracardiac thrombus… 
1986
1986
High-level amikacin resistance in Escherichia coli due to phosphorylation and impaired aminoglycoside uptake
Plasmid pMP1-1 in Escherichia coli L-0 encodes aminoglycoside (AG) 3'-phosphotransferase II [APH(3')-II]. This enzyme modifies… 
Review
1986
Review
1986
Survey of aminoglycoside resistance patterns.
We studied the susceptibility of 545 gram-negative clinical isolates to six aminoglycosides: gentamicin, tobramycin, netilmicin… 
1983
1983
Serum bactericidal activity of ceftazidime and cefoperazone alone or in combination with amikacin against Pseudomonas aeruginosa and Klebsiella pneumoniae
Sera of volunteers receiving ceftazidime (2 g) or amikacin (500 mg), alone or in combination, or cefoperazone (2, 4, or 6 g) or… 
1982
1982
Inactivation of amikacin and gentamicin by carbenicillin in patients with end-stage renal failure
Aminoglycosides are inactivated by carbenicillin in vitro and in patients with end-stage renal failure. In vitro, amikacin is… 
1980
1980
Prospective comparative study of efficacy and toxicity of netilmicin and amikacin
Eighty patients were treated with either amikacin or netilmicin in a prospective randomized study of serious gram-negative… 
Highly Cited
1979
Highly Cited
1979
Effect of Time and Concentration Upon Interaction Between Gentamicin, Tobramycin, Netilmicin, or Amikacin and Carbenicillin or Ticarcillin
An aminoglycoside antibiotic and carbenicillin or ticarcillin are widely used in the treatment of patients with gram-negative… 
1977
1977
Comparison of amikacin and tobramycin in the treatment of infection in patients with cancer.
Two new aminoglycoside antibiotics, tobramycin and amikacin, were compared in a randomized study of the treatment of infections… 
Highly Cited
1976
Highly Cited
1976
Comparative Activity of Netilmicin, Gentamicin, Amikacin, and Tobramycin Against Pseudomonas aeruginosa and Enterobacteriaceae
Netilmicin (Sch 20569), a semisynthetic aminoglycoside antibiotic, was compared with gentamicin, tobramycin, and amikacin against… 
Highly Cited
1975
Highly Cited
1975
Amikacin therapy of infections in neutropenic patients
Amikacin, a new aminoglycoside antibiotic, was utilized in the treatment of 49 cases of infection which occurred in 39…