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Amdray

National Institutes of Health

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SDZ PSC 833

Papers overview

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2017
2017
Cremophor EL Alters the Plasma Protein Binding and Pharmacokinetic Profile of Valspodar in Rats
Abstract Cremophor EL is a nonionic surfactant widely used in pharmaceutical formulations. Nonetheless, there are several reports… 
Highly Cited
2006
Highly Cited
2006
Rapid Modulation of P-Glycoprotein-Mediated Transport at the Blood-Brain Barrier by Tumor Necrosis Factor-α and Lipopolysaccharide
At the blood-brain barrier, P-glycoprotein, an ATP-driven drug efflux pump, selectively limits drug access to the brain… 
Highly Cited
2000
Highly Cited
2000
P-Glycoprotein inhibitor valspodar (PSC 833) increases the intracellular concentrations of daunorubicin in vivo in patients with P-glycoprotein-positive acute myeloid leukemia.
PURPOSE The aim of the present study was to evaluate the effect of the cyclosporine derivative valspodar (PSC 833; Amdray… 
Review
1999
Review
1999
Valspodar: current status and perspectives.
Valspodar (Amdray, SDZ PSC 833) is derived from cyclosporin, but lacks the immunosuppressive and most of the collateral… 
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