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Amdinocillin

Known as: Amdinocillin [Chemical/Ingredient], Penicillin Hx, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- 
A semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (4)

Amdinocillin PivoxilFL-1060Selexidbacmecillinam

Broader (2)

Anti-Bacterial AgentsAnti-Infective Agents, Urinary
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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2003
2003
Distinct penicillin binding proteins involved in the division , elongation , and shape of Escherichia coli K 12 ( P-lactam antibiotics / slab gel electrophoresis / binding protein mutants )
The varied effects of #-lactam antibiotics on cell division, cell elongation, and cell shape in E. coil are shown to be due to… 
1988
1988
Turgor pressure responses of a gram-negative bacterium to antibiotic treatment, measured by collapse of gas vesicles
The internal hydrostatic pressure of Ancylobacter aquaticus was measured by collapsing the gas vesicles with an externally… 
1987
1987
Studies on prodrugs. VI. Preparation and characterization of (5-substituted 2-oxo-1,3-dioxol-4-yl)methyl esters of mecillinam.
Mecillinam is a unique penicillin derivative which exhibits strong antimicrobial activities against Escherichia coli and other… 
1985
1985
Formadicins, new monocyclic beta-lactam antibiotics of bacterial origin. I. Taxonomy, fermentation and biological activities.
A Gram-negative bacterium produces new monocyclic beta-lactam antibiotics with a formylamino substituent, named formadicins A, B… 
1985
1985
Antibiotic treatment of neonates--does route of administration matter?
The pharmacokinetics of gentamicin (19 babies), benzylpenicillin (7 babies), mecillinam (15 babies), cefuroxime (15 babies… 
1984
1984
Chromosomal loci associated with antibiotic hypersensitivity in pulmonary isolates of Pseudomonas aeruginosa.
492a and 492c were two strains of Pseudomonas aeruginosa isolated from the sputum of a patient with cystic fibrosis. The strains… 
1979
1979
Effect of serum and blood on Enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin and mecillinam.
Bacteria from the strains of five species of Enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of… 
1977
1977
In vitro studies with mecillinam on Escherichia coli and Pseudomonas aeruginosa.
The ability of a beta-lactam antibiotic to inhibit the growth of Gram-negative bacteria depends on three main properties: ting… 
1977
1977
Laboratory studies on mecillinam: activity alone and combined with cephradine.
Mecillinam (MC) was found to be inhibitory at low concentrations to a wide range of Gram-negative bacteria; the sensitivity of… 
1977
1977
The treatment of enteric fever with mecillinam.
In vitro studies carried out in this Department confirmed the high activity of mecillinam against Salmonella spp. As a result we…