Alprenolol

Known as: Aprenololo, Alprenololum, (RS)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol 
One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
G protein-coupled receptors (GPCRs) represent a large fraction of current pharmaceutical targets, and of the GPCRs, the beta(2… (More)
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Highly Cited
2008
Highly Cited
2008
Recent evidence suggests that binding of agonist to its cognate receptor initiates not only classical G protein-mediated… (More)
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Review
2007
Review
2007
Astrocytic energy demand is stimulated by K(+) and glutamate uptake, signaling processes, responses to neurotransmitters, Ca(2… (More)
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Highly Cited
1997
Highly Cited
1997
Although many β1-receptor antagonists and β2-receptor agonists have been used in pharmacotherapy for many years their… (More)
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Highly Cited
1994
Highly Cited
1994
Agonist-independent properties of the human beta 2-adrenergic receptor (beta 2AR) were studied using the baculovirus expression… (More)
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Highly Cited
1986
Highly Cited
1986
Agonist-promoted desensitization of adenylate cyclase is intimately associated with phosphorylation of the beta-adrenergic… (More)
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Review
1984
Review
1984
First-pass elimination takes place when a drug is metabolised between its site of administration and the site of sampling for… (More)
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1976
1976
Human lymphocytes are known to posessess a catecholamine-responsive adenylate cyclase which has typical beta-adrenergic… (More)
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Highly Cited
1975
Highly Cited
1975
Adrenergic beta-blocking agents were given to 7 patients with advanced congestive cardiomyopathy who had tachycardia at rest (98… (More)
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1975
1975
(Minus) [3-H] alprenolol, a potent beta-adrenergic antagonist, was used to identify binding sites in a fraction of canine… (More)
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