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Alpha protein

Protein which consists of alpha helices.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
TRIF Signaling Stimulates Translation of TNF-α mRNA via Prolonged Activation of MK2
The adapter protein TRIF mediates signal transduction through TLR3 and TLR4, inducing production of type I IFNs and inflammatory… 
Highly Cited
2009
Highly Cited
2009
Breast cancer cell growth inhibition by phenethyl isothiocyanate is associated with down-regulation of oestrogen receptor-α36
The dietary isothiocyanates (ITCs) exhibit strong chemopreventive activities for a variety of neoplasms including breast cancer… 
Highly Cited
2006
Highly Cited
2006
Hypoxia-Inducible Factor-1-Dependent and -Independent Regulation of Insulin-Like Growth Factor-1-Stimulated Vascular Endothelial Growth Factor Secretion
Hypoxia-induced stress plays a central role in retinal vascular disease and cancer. Increased hypoxia-inducible factor-1α (Hif-1… 
Highly Cited
2005
Highly Cited
2005
Phenotypic persistence after reoxygenation of hypoxic neuroblastoma cells
Fast‐growing solid tumors are usually insufficiently vascularized, leading to areas with necrosis and/or poorly oxygenated cells… 
Highly Cited
2000
Highly Cited
2000
Down-regulation by troglitazone of hepatic tumor necrosis factor-alpha and interleukin-6 mRNA expression in a murine model of non-insulin-dependent diabetes.
Highly Cited
1999
Highly Cited
1999
Meltrin-alpha, a fusion protein involved in multinucleated giant cell and osteoclast formation.
The formation of multinucleated cells such as myotubes, macrophage-derived giant cells (MGC), and osteoclasts is the result of… 
Highly Cited
1994
Highly Cited
1994
Bombesin, platelet-derived growth factor, and diacylglycerol induce selective membrane association and down-regulation of protein kinase C isotypes in Swiss 3T3 cells.
Highly Cited
1992
Highly Cited
1992
Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells.
The expression of a molecular cDNA clone (P1 KIN) of the human RNA-dependent P1/eIF-2 alpha protein kinase (PKR) was examined in… 
Highly Cited
1991
Highly Cited
1991
Molecular genetic analysis of two G alpha protein subunits in Dictyostelium.
In Dictyostelium, chemotaxis to folate during growth and cAMP during aggregation is controlled via cell surface receptors. To… 
Highly Cited
1989
Highly Cited
1989
Regulation and function of G alpha protein subunits in Dictyostelium.
We have examined the developmental regulation and function of two G alpha protein subunits, G alpha 1 and G alpha 2, from… 
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