Alkylphosphocholine Compound

Known as: Alkylphospholipid, APC, Alkylphospholipids 
An ether-linked lysophosphatidylcholine with potential antineoplastic activity. Exhibiting anti-proliferative and immunomodulatory properties, alkyl… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2018
024619952018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Many solid tumors contain an overabundance of phospholipid ethers relative to normal cells. Capitalizing on this difference, we… (More)
Is this relevant?
2010
2010
Alkylphospholipids and alkylphosphocholines (APCs) are promising antitumor agents, which target the plasma membrane and affect… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
2010
2010
BACKGROUND HIV-1 infected macrophages and microglia are long-lived viral reservoirs persistently producing viral progenies. HIV-1… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
BACKGROUND AND PURPOSE Alkylphospholipid (APL) analogues constitute a new class of synthetic anti-tumour agents that act directly… (More)
Is this relevant?
2008
2008
Synthetic alkylphospholipids (APLs), such as edelfosine, miltefosine and perifosine, constitute a new class of antineoplastic… (More)
Is this relevant?
2004
2004
Alkylphospholipids (ALKs) are a novel class of antitumor agents with an unknown mechanism of action. The first ALK tested in the… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2004
2004
AbstractAlkylphosphocholines (APC) are candidate anticancer agents. We here report that APC induce the formation of large… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2003
2003
Alkylphospholipids, such as the antitumor ether lipid 1-O-octadecyl-2-O-methylglycero-3-phosphocholine, modulate cancer cell… (More)
Is this relevant?
1995
1995
The human histiocytic cell line U937, which expresses a number of monocyte markers and properties, was investigated with regard… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?