Aldosterone

Known as: (+)-Aldosterone, Aldosterone [Chemical/Ingredient], Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)- 
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of severe hypertension, feature constitutive… (More)
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Highly Cited
2005
Highly Cited
2005
The renin-angiotensin-aldosterone system has been causally implicated in obesity-associated hypertension. We studied the… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Primary hyperaldosteronism is a well-recognized cause of secondary hypertension. It is unknown whether serum… (More)
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Highly Cited
2003
Highly Cited
2003
It has been reported that continuous ACE inhibitor therapy does not necessarily produce a maintained decrease in plasma… (More)
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Highly Cited
2002
Highly Cited
2002
Vascular inflammation was examined as a potential mechanism of aldosterone-mediated myocardial injury in uninephrectomized rats… (More)
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Highly Cited
2000
Highly Cited
2000
To determine the role of aldosterone in mediating cardiovascular damage, we performed ablation/replacement experiments with… (More)
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Highly Cited
1999
Highly Cited
1999
Sodium homeostasis in terrestrial and freshwater vertebrates is controlled by the corticosteroid hormones, principally… (More)
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Highly Cited
1999
Highly Cited
1999
Aldosterone stimulates sodium transport in the renal collecting duct by activating the epithelial sodium channel (ENaC). To… (More)
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Review
1991
Review
1991
Left ventricular hypertrophy (LVH) is the major risk factor associated with myocardial failure. An explanation for why a… (More)
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