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Aldosterone

Known as: (+)-Aldosterone, Aldosterone [Chemical/Ingredient], Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)- 
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (14)

18,21-anhydroaldosterone18-deoxyaldosterone19-hydroxyaldosterone19-noraldosterone
Adrenal CortexAldosterone AntagonistsAldosterone ReceptorsAldosterone measurement

Broader (2)

Adrenal Cortex HormonesMineralocorticoids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1979
Highly Cited
1979
Activation of a Prorenin‐Like Substance in Human Plasma by Trypsin and by Urinary Kallikrein
SUMMARY Inactive plasma renin (a prorenlp-like substance) can be activated by trypsin. There are also endogenous neutral serine… 
Highly Cited
1978
Highly Cited
1978
Aldosterone Responsiveness in Patients with Diabetes Mellitus
Plasma aldosterone (PA) and plasma renin activity (PRA) were determined in 44 diabetics, of whom nine were normotensive but not… 
Highly Cited
1978
Highly Cited
1978
The Kallikrein‐Kinin System and Prostaglandins in the Kidney: Their Relation to Furosemide‐Induced Diuresis and to the Renin‐Angiotensin‐Aldosterone System in Man
The relations among the renin-angiotensin-aldosterone system, renal prostaglandin E, the renal kallikrein-kinin system, and… 
Highly Cited
1973
Highly Cited
1973
A radioimmunoassay for plasma aldosterone without chromatography.
A radioimmunoassay for plasma aldosterone has been developed which requires no preliminary chromatography. Purification consists… 
1968
1968
Aldosterone deficiency in chronic renal failure.
A case of isolated hypoaldosteronism associated with chronic renal failure is reported. Potassium retention and hyperkalemia… 
Highly Cited
1967
Highly Cited
1967
Measurement of aldosterone in peripheral blood of man and sheep.
ABSTRACT A double isotope derivative dilution procedure is described for the measurement of aldosterone in peripheral blood of… 
Highly Cited
1965
Highly Cited
1965
ROLE OF 18-HYDROXYLATION IN THE BIOSYNTHESIS OF ALDOSTERONE.
The role of 18-hydroxylation in the biosynthesis of aldosterone from corticosterone was investigated by incubating radioactive 18… 
Highly Cited
1961
Highly Cited
1961
Angiotensin, aldosterone and human arterial hypertension.
  • J. Genest
  • Canadian Medical Association journal
  • 1961
  • Corpus ID: 43855611
THIS ARTICLE outlines the history of the continuous pursuit of a research problem throughout a 12-year period and will be… 
Highly Cited
1957
Highly Cited
1957
Chemical method for the determination of urinary aldosterone.
A new method of purification of crude neutral extracts of urine for the isolation and determination of aldosterone is presented… 
Highly Cited
1956
Highly Cited
1956
Physicochemical estimation of aldosterone in urine.
We have recently described (2) the essential features of a physicochemical method for the specific determination of aldosterone…