Aldosterone

Known as: (+)-Aldosterone, Aldosterone [Chemical/Ingredient], Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)- 
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to… (More)
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (12)

18,21-anhydroaldosterone18-deoxyaldosterone19-hydroxyaldosterone19-noraldosterone
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Adrenal CortexAldosterone AntagonistsAldosterone ReceptorsAldosterone measurement
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Broader (2)

Adrenal Cortex HormonesMineralocorticoids

Papers overview

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Highly Cited
2011
Highly Cited
2011
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension.
Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of severe hypertension, feature constitutive… (More)
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Highly Cited
2005
Highly Cited
2005
Weight loss and the renin-angiotensin-aldosterone system.
The renin-angiotensin-aldosterone system has been causally implicated in obesity-associated hypertension. We studied the… (More)
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Highly Cited
2004
Highly Cited
2004
Serum aldosterone and the incidence of hypertension in nonhypertensive persons.
BACKGROUND Primary hyperaldosteronism is a well-recognized cause of secondary hypertension. It is unknown whether serum… (More)
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Highly Cited
2003
Highly Cited
2003
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction.
 
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Highly Cited
2003
Highly Cited
2003
Effectiveness of aldosterone blockade in patients with diabetic nephropathy.
It has been reported that continuous ACE inhibitor therapy does not necessarily produce a maintained decrease in plasma… (More)
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Highly Cited
2002
Highly Cited
2002
Aldosterone induces a vascular inflammatory phenotype in the rat heart.
Vascular inflammation was examined as a potential mechanism of aldosterone-mediated myocardial injury in uninephrectomized rats… (More)
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Highly Cited
2000
Highly Cited
2000
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
To determine the role of aldosterone in mediating cardiovascular damage, we performed ablation/replacement experiments with… (More)
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Highly Cited
1999
Highly Cited
1999
Epithelial sodium channel regulated by aldosterone-induced protein sgk.
Sodium homeostasis in terrestrial and freshwater vertebrates is controlled by the corticosteroid hormones, principally… (More)
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Highly Cited
1999
Highly Cited
1999
Aldosterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney.
Aldosterone stimulates sodium transport in the renal collecting duct by activating the epithelial sodium channel (ENaC). To… (More)
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Review
1991
Review
1991
Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.
Left ventricular hypertrophy (LVH) is the major risk factor associated with myocardial failure. An explanation for why a… (More)
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