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Aldosterone

Known as: (+)-Aldosterone, Aldosterone [Chemical/Ingredient], Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)- 
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (14)

18,21-anhydroaldosterone18-deoxyaldosterone19-hydroxyaldosterone19-noraldosterone
Adrenal CortexAldosterone AntagonistsAldosterone ReceptorsAldosterone measurement

Broader (2)

Adrenal Cortex HormonesMineralocorticoids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Gender and the renin–angiotensin–aldosterone system
Premenopausal women are protected to some extent from cardiovascular and kidney diseases. Because this protection weakens after… 
Highly Cited
2004
Highly Cited
2004
Possible Contributions of Reactive Oxygen Species and Mitogen-Activated Protein Kinase to Renal Injury in Aldosterone/Salt-Induced Hypertensive Rats
Abstract—Studies were performed to test the hypothesis that reactive oxygen species (ROS) and mitogen-activated protein kinase… 
Review
2001
Review
2001
Aldosterone in congestive heart failure.
The potent mineralocorticoid aldosterone has a multifaceted role in the pathogenesis of congestive heart failure. In addition to… 
Highly Cited
1999
Highly Cited
1999
Aldosterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney.
Aldosterone stimulates sodium transport in the renal collecting duct by activating the epithelial sodium channel (ENaC). To… 
Review
1985
Review
1985
Atrial natriuretic hormone, the renin-aldosterone axis, and blood pressure-electrolyte homeostasis.
The renin-angiotensin-aldosterone axis exerts major control over sodium and potassium balance and arterial blood pressure. These… 
Highly Cited
1985
Highly Cited
1985
RENAL, HAEMODYNAMIC, AND HORMONAL EFFECTS OF HUMAN ALPHA ATRIAL NATRIURETIC PEPTIDE IN HEALTHY VOLUNTEERS
Highly Cited
1984
Highly Cited
1984
Inhibition of aldosterone production by an atrial extract.
Crude extracts of rat atria reduced the basal amount of aldosterone released from rat zona glomerulosa cells and partially… 
Highly Cited
1970
Highly Cited
1970
Drinking induced by injection of angiotensin into the brain of the rat
1. When applied directly to the brain, angiotensin II amide, as either the valine5 octapeptide, causes rats in normal fluid… 
Highly Cited
1968
Highly Cited
1968
Amiloride: a potent inhibitor of sodium transport across the toad bladder
1 Amiloride inhibits Na transport and short‐circuit current (SCC) across the toad bladder. It is 1000 times more active at the… 
Highly Cited
1968
Highly Cited
1968
Extraction of steroid conjugates with a neutral resin.
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