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Aldosterone

Known as: (+)-Aldosterone, Aldosterone [Chemical/Ingredient], Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)- 
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (14)

18,21-anhydroaldosterone18-deoxyaldosterone19-hydroxyaldosterone19-noraldosterone
Adrenal CortexAldosterone AntagonistsAldosterone ReceptorsAldosterone measurement

Broader (2)

Adrenal Cortex HormonesMineralocorticoids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1983
Highly Cited
1983
Biosynthesis of 18-oxocortisol by aldosterone-producing adrenal tissue.
Aldosterone-biosynthesizing adrenal tissue contains an angular methyl oxidase which converts corticosterone to 18… 
Highly Cited
1979
Highly Cited
1979
Activation of a Prorenin‐Like Substance in Human Plasma by Trypsin and by Urinary Kallikrein
SUMMARY Inactive plasma renin (a prorenlp-like substance) can be activated by trypsin. There are also endogenous neutral serine… 
Highly Cited
1979
Highly Cited
1979
Converting Enzyme Inhibition with an Orally Active Compound in Hypertensive Man
SUMMARY The short-terra cardiovascular and endocrine effects of an orally active anglotensin converting enzyme inhibitor, SQ14… 
Review
1978
Review
1978
The defense against hyperkalemia: the roles of insulin and aldosterone.
POTASSIUM homeostasis can be conveniently divided into two inter-related systems: external and internal potassium balance… 
Highly Cited
1978
Highly Cited
1978
Aldosterone Responsiveness in Patients with Diabetes Mellitus
Plasma aldosterone (PA) and plasma renin activity (PRA) were determined in 44 diabetics, of whom nine were normotensive but not… 
Highly Cited
1977
Highly Cited
1977
Disparate patterns of aldosterone response during diuretic treatment of hypertension.
In 50 patients with essential hypertension treated with chlorthalidone, 100 mg daily for 6 weeks, treatment responders (fall in… 
Highly Cited
1968
Highly Cited
1968
Electrical potential and short circuit current of an in vitro preparation of rat colon mucosa
1. Using a preparation of rat colon mucosa mounted in vitro in small chambers, some factors which influence the electrical… 
Highly Cited
1967
Highly Cited
1967
Measurement of aldosterone in peripheral blood of man and sheep.
ABSTRACT A double isotope derivative dilution procedure is described for the measurement of aldosterone in peripheral blood of… 
Highly Cited
1961
Highly Cited
1961
Angiotensin, aldosterone and human arterial hypertension.
  • J. Genest
  • Canadian Medical Association journal
  • 1961
  • Corpus ID: 43855611
THIS ARTICLE outlines the history of the continuous pursuit of a research problem throughout a 12-year period and will be… 
Highly Cited
1956
Highly Cited
1956
Physicochemical estimation of aldosterone in urine.
We have recently described (2) the essential features of a physicochemical method for the specific determination of aldosterone…