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Aldosterone

Known as: (+)-Aldosterone, Aldosterone [Chemical/Ingredient], Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)- 
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (14)

18,21-anhydroaldosterone18-deoxyaldosterone19-hydroxyaldosterone19-noraldosterone
Adrenal CortexAldosterone AntagonistsAldosterone ReceptorsAldosterone measurement

Broader (2)

Adrenal Cortex HormonesMineralocorticoids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting… 
Highly Cited
2020
Highly Cited
2020
Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19
Abstract Background There is concern about the potential of an increased risk related to medications that act on the renin… 
Highly Cited
2011
Highly Cited
2011
K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension
Potassium channel mutations drive both cell growth and hormone production in an adrenal tumor that causes severe hypertension… 
Review
2007
Review
2007
The renin-angiotensin aldosterone system: pathophysiological role and pharmacologic inhibition.
  • S. Atlas
  • Journal of Managed Care Pharmacy
  • 2007
  • Corpus ID: 6171863
BACKGROUND The renin-angiotensin aldosterone system (RAAS) is a hormonal cascade that functions in the homeostatic control of… 
Highly Cited
2003
Highly Cited
2003
Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction
background Aldosterone blockade reduces mortality and morbidity among patients with severe heart failure. We conducted a double… 
Review
2000
Review
2000
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.
The secretion of glucocorticoids (GCs) is a classic endocrine response to stress. Despite that, it remains controversial as to… 
Highly Cited
1999
Highly Cited
1999
Epithelial sodium channel regulated by aldosterone-induced protein sgk.
Sodium homeostasis in terrestrial and freshwater vertebrates is controlled by the corticosteroid hormones, principally… 
Highly Cited
1992
Highly Cited
1992
A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
GLUCOCORTICOID-REMEDIABLE Received 26 September; accepted 29 October 1991.aldosteronism (GRA), an autosomal dominant disorder, is… 
Review
1991
Review
1991
Pathological Hypertrophy and Cardiac Interstitium: Fibrosis and Renin‐Angiotensin‐Aldosterone System
Left ventricular hypertrophy (LVH) is the major risk factor associated with myocardial failure. An explanation for why a… 
Highly Cited
1973
Highly Cited
1973
Plasma aldosterone regulation in anephric man.
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