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Aldosterone
Known as:
(+)-Aldosterone
, Aldosterone [Chemical/Ingredient]
, Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)-
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to…
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National Institutes of Health
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Related topics
Related topics
39 relations
Narrower (14)
18,21-anhydroaldosterone
18-deoxyaldosterone
19-hydroxyaldosterone
19-noraldosterone
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Adrenal Cortex
Aldosterone Antagonists
Aldosterone Receptors
Aldosterone measurement
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Broader (2)
Adrenal Cortex Hormones
Mineralocorticoids
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
M. Vaduganathan
,
O. Vardeny
,
T. Michel
,
J. McMurray
,
M. Pfeffer
,
S. Solomon
New England Journal of Medicine
2020
Corpus ID: 214732444
RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting…
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Highly Cited
2020
Highly Cited
2020
Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19
H. Reynolds
,
S. Adhikari
,
+13 authors
J. Hochman
New England Journal of Medicine
2020
Corpus ID: 218469674
Abstract Background There is concern about the potential of an increased risk related to medications that act on the renin…
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Highly Cited
2011
Highly Cited
2011
K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension
Murim Choi
,
U. Scholl
,
+17 authors
R. Lifton
Science
2011
Corpus ID: 1517625
Potassium channel mutations drive both cell growth and hormone production in an adrenal tumor that causes severe hypertension…
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Review
2007
Review
2007
The renin-angiotensin aldosterone system: pathophysiological role and pharmacologic inhibition.
S. Atlas
Journal of Managed Care Pharmacy
2007
Corpus ID: 6171863
BACKGROUND The renin-angiotensin aldosterone system (RAAS) is a hormonal cascade that functions in the homeostatic control of…
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Highly Cited
2003
Highly Cited
2003
Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction
B. Pitt
,
W. Remme
,
+7 authors
M. Gatlin
2003
Corpus ID: 73330226
background Aldosterone blockade reduces mortality and morbidity among patients with severe heart failure. We conducted a double…
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Review
2000
Review
2000
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.
R. Sapolsky
,
L. Romero
,
A. Munck
Endocrine reviews
2000
Corpus ID: 13462266
The secretion of glucocorticoids (GCs) is a classic endocrine response to stress. Despite that, it remains controversial as to…
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Highly Cited
1999
Highly Cited
1999
Epithelial sodium channel regulated by aldosterone-induced protein sgk.
S. Y. Chen
,
A. Bhargava
,
+6 authors
D. Pearce
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 2208064
Sodium homeostasis in terrestrial and freshwater vertebrates is controlled by the corticosteroid hormones, principally…
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Highly Cited
1992
Highly Cited
1992
A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
R. Lifton
,
R. Dluhy
,
+4 authors
J. Lalouel
Nature
1992
Corpus ID: 4321924
GLUCOCORTICOID-REMEDIABLE Received 26 September; accepted 29 October 1991.aldosteronism (GRA), an autosomal dominant disorder, is…
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Review
1991
Review
1991
Pathological Hypertrophy and Cardiac Interstitium: Fibrosis and Renin‐Angiotensin‐Aldosterone System
K. Weber
,
C. Brilla
Circulation
1991
Corpus ID: 46567297
Left ventricular hypertrophy (LVH) is the major risk factor associated with myocardial failure. An explanation for why a…
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Highly Cited
1973
Highly Cited
1973
Plasma aldosterone regulation in anephric man.
W. G. Walker
,
C. R. Cooke
Kidney International
1973
Corpus ID: 41671930
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