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Aldosterone Receptors

Known as: Aldosterone Receptor, Receptor, Aldosterone, Receptors, Aldosterone 
Cytoplasmic proteins that specifically bind aldosterone and mediate its cellular effects. The aldosterone-bound receptor acts in the nucleus to… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The extracellular matrix (ECM) is a living network of proteins that maintains the structural integrity of the myocardium and… Expand
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Review
2012
Review
2012
Aldosterone exerts direct effects on the vascular system by inducing oxidative stress, inflammation, hypertrophic remodeling… Expand
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Highly Cited
2007
Highly Cited
2007
Accumulating evidence suggests that mineralocorticoid receptor blockade effectively reduces proteinuria in hypertensive patients… Expand
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Highly Cited
2006
Highly Cited
2006
The antiepileptic drug carbamazepine (CBZ) is a potent inducer of human drug metabolism, resulting in serious interactions with… Expand
Highly Cited
2004
Highly Cited
2004
The importance of aldosterone in the pathophysiology of chronic heart failure (HF) has been established in previous studies [1–4… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND METHODS Aldosterone is important in the pathophysiology of heart failure. In a doubleblind study, we enrolled 1663… Expand
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Highly Cited
1983
Highly Cited
1983
The two [3H]aldosterone-binding proteins of rat brain cytosol were characterized by a dextran-coated charcoal method. With… Expand
Highly Cited
1976
Highly Cited
1976
The existence of high and low affinity mineralocorticoid-binding macromolecules (receptors) has been demonstrated in vitro in… Expand
Highly Cited
1974
Highly Cited
1974
In vivo, a spirolactone (SC-26304) inhibited the effects of aldosterone on urinary K(+):Na(+) ratios and the binding of [(3)H… Expand
Highly Cited
1974
Highly Cited
1974
Abstract The currently accepted hypothesis of the anti-mineralocorticoid action of spirolactones is that of competition for… Expand