Skip to search formSkip to main contentSkip to account menu

Aganglionosis, Colonic

Known as: Colonic Aganglionosis, TCA, Total colonic aganglionosis 
The severe form of Hirschsprung disease, this is characterized by a complete lack of nerve cells in the large intestine, and often a partial lack in… 
National Institutes of Health

Related topics

Related topics

16 relations
Acquired megacolonAganglionosis, Rectosigmoid ColonColon structure (body structure)Fryns syndrome

Broader (8)

Colonic DiseasesCongenital Digestive System DisorderCongenital DisordersCongenital absence

Narrower (1)

Total intestinal aganglionosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications.
Diabetes is associated with altered cellular metabolism, but how altered metabolism contributes to the development of diabetic… 
Highly Cited
2015
Highly Cited
2015
Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies.
Highly Cited
2014
Highly Cited
2014
Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia.
Nonalcoholic fatty liver disease (NAFLD) spectrum disorders affect approximately 1 billion individuals worldwide. However, the… 
Highly Cited
2008
Highly Cited
2008
Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.
Mutations in the RET gene are the primary cause of Hirschsprung disease (HSCR), or congenital intestinal aganglionosis. However… 
Review
2005
Review
2005
RET tyrosine kinase signaling in development and cancer.
Highly Cited
2004
Highly Cited
2004
Severe adverse drug reactions of antidepressants: results of the German multicenter drug surveillance program AMSP.
The goal of the German drug safety program in psychiatry AMSP (Arzneimittelsicherheit in der Psychiatrie) is the assessment of… 
Highly Cited
1997
Highly Cited
1997
Are SSRIs better than TCAs? Comparison of SSRIs and TCAs: A meta‐analysis
In this analysis we examined studies of tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) to… 
Highly Cited
1995
Highly Cited
1995
A lack of intestinal pacemaker (c-kit) in aganglionic bowel of patients with Hirschsprung's disease.
Highly Cited
1991
Highly Cited
1991
First direct demonstration of preferential release of citrate from astrocytes using [13C]NMR spectroscopy of cultured neurons and astrocytes
Highly Cited
1983
Highly Cited
1983
Duration of circulatory arrest does influence the psychological development of children after cardiac operation in early life.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)