Adenovirus serotype
National Institutes of Health
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Adenoviral vectors have long been forerunners in the development of effective CD8 T cell–based vaccines; therefore, it is…
Pre-existing immunity (PEI) to human adenovirus serotype 5 (Ad5) worldwide is the primary limitation to routine clinical use of…
The use of anticancer therapeutic agents is limited largely by their severe toxicity to normal tissues. The development of novel…
ABSTRACT Efforts to develop adenovirus vectors suitable for genetic interventions in humans have identified three major…
The capacity of gene delivery vehicles is considered to be a critical factor determining the success of gene therapy. To date…
Human adenovirus serotype 5 (HAd5) infect dendritic cells with low efficiency which restricts the use of HAd5 as an antigen…
The 36,001 base pair DNA sequence of human adenovirus serotype 1 (HAdV-1) has been determined, using a 'leveraged primer…
The efficiency of human adenovirus serotype 5 (Ad5) transgene delivery was tested on several human and animal cell lines in vitro…
Recombinant human adenovirus serotype 2 proteinase (both native and selenomethionine‐substituted) has been crystallized in the…