Acute quadriplegic myopathy
National Institutes of Health
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Non‐technical summary Wasting and severely impaired function of skeletal muscle is frequently observed in critically ill…
BackgroundAcute quadriplegic myopathy (AQM) or critical illness myopathy (CIM) is frequently observed in intensive care unit (ICU…
Acquired neuromuscular disorders have been shown to be very common in critically ill patients receiving prolonged mechanical…
Background: The mechanisms underlying acute quadriplegic myopathy (AQM) are poorly understood, partly as a result of the fact…
We previously demonstrated that muscle fibers become unable to fire action potentials in both patients and an animal model of…
We investigated the changes of muscle proteins in acute quadriplegic myopathy (AQM) using immunohistochemistry and stoichiometry…
Objective: Long‐term treatment with nondepolarizing neuromuscular blocking agents and corticosteroids in the intensive care unit…
BACKGROUND
In the last few years, rare cases of acute quadriplegic myopathy (AQM*) with myosin-deficient muscle fibres occurring…
In rats treated with high‐dose corticosteroids, skeletal muscle that is denervated in vivo (steroid‐denervated [S‐D]) develops…
We have previously found that muscle is electrically inexcitable in severe acute quadriplegic myopathy (AQM). In contrast, muscle…