• Publications
  • Influence
A comprehensive classification system for lipids11 The evaluation of this manuscript was handled by the former Editor-in-Chief Trudy Forte. Published, JLR Papers in Press, February 16, 2005. DOI
Lipids are produced, transported, and recognized by the concerted actions of numerous enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules, “lipidomics,” in theExpand
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Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors
Nuclear receptors (NRs) repress transcriptional responses to diverse signaling pathways as an essential aspect of their biological activities, but mechanisms determining the specificity andExpand
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LMSD: LIPID MAPS structure database
TLDR
The LIPID MAPS Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids. Expand
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Lipidomics reveals a remarkable diversity of lipids in human plasma1[S]
The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid analysis is now aExpand
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LIPID MAPS online tools for lipid research
TLDR
The LIPID MAPS consortium has developed a number of online tools for performing tasks such as drawing lipid structures and predicting possible structures from mass spectrometry (MS) data. Expand
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Pairwise Alignment of Protein Interaction Networks
TLDR
We propose a mathematical model that extends the concepts of match, mismatch, and gap in sequence alignment and evaluates similarity between graph structures through a scoring function that accounts for evolutionary events. Expand
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Reconstruction of cellular signalling networks and analysis of their properties
The study of cellular signalling over the past 20 years and the advent of high-throughput technologies are enabling the reconstruction of large-scale signalling networks. After careful reconstructionExpand
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Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses
Inflammation and macrophage foam cells are characteristic features of atherosclerotic lesions, but the mechanisms linking cholesterol accumulation to inflammation and LXR-dependent response pathwaysExpand
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A comprehensive classification system for lipids.
Lipids are produced, transported, and recognized by the concerted actions of numerous enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules, "lipidomics," in theExpand
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MicroRNA-21 targets peroxisome proliferators-activated receptor-α in an autoregulatory loop to modulate flow-induced endothelial inflammation
  • J. Zhou, K. Wang, +5 authors S. Chien
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2 June 2011
Adhesion of circulating monocytes to vascular endothelial cells (ECs) is a critical event leading to vascular inflammation and, hence, development of atherosclerosis. MicroRNAs (miRs) are a class ofExpand
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