Acute Undifferentiated Leukemia

Known as: Acute Leukemia Not Otherwise Specified, Leukemia Stem Cell, Undifferentiated Acute Leukemia 
A rare acute leukemia of ambiguous lineage in which the blasts do not express markers specific to myeloid or lymphoid lineage.
National Institutes of Health

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11 relations
AgranulocytosisAnemiaBone MarrowBone marrow stem cell
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Broader (1)

Undifferentiated leukemia

Papers overview

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Review
2017
Review
2017
The chronic myeloid leukemia stem cell: stemming the tide of persistence.
Chronic myeloid leukemia (CML) is caused by the acquisition of the tyrosine kinase BCR-ABL1 in a hemopoietic stem cell… (More)
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Highly Cited
2012
Highly Cited
2012
The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.
Using a mouse model of human MLL-AF9 leukemia, we identified the lysine-specific demethylase KDM1A (LSD1 or AOF2) as an essential… (More)
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Highly Cited
2007
Highly Cited
2007
Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
Oncogenic mutations of the MLL histone methyltransferase confer an unusual ability to transform non-self-renewing myeloid… (More)
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Highly Cited
2004
Highly Cited
2004
Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium.
Tumor growth is dependent in part on "neoangiogenesis." Functional involvement of bone marrow (BM)-derived cells in this process… (More)
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Highly Cited
2000
Highly Cited
2000
SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-Tα chain expression
Cooperation between the stem cell leukemia (SCL) transcription factor and its nuclear partners LMO1 or LMO2 induces aggressive T… (More)
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Highly Cited
1998
Highly Cited
1998
Wilms' tumor (WT1) gene mutations occur mainly in acute myeloid leukemia and may confer drug resistance.
In a previous study of acute leukemia, we have shown that WT1 gene mutations occur in both myeloid and biphenotypic subtypes… (More)
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Highly Cited
1996
Highly Cited
1996
Biochemical and genetic characterization of enterocin A from Enterococcus faecium, a new antilisterial bacteriocin in the pediocin family of bacteriocins.
A new bacteriocin has been isolated from an Enterococcus faecium strain. The bacteriocin, termed enterocin A, was purified to… (More)
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Review
1990
Review
1990
Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia.
The National Cancer Institute (NCI) sponsored a workshop to develop a set of standardized diagnostic and response criteria for… (More)
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1988
1988
Heterogeneity in acute undifferentiated leukemia.
From January 1985 to May 1987, we studied 256 adults with newly diagnosed acute leukemia. Acute undifferentiated leukemia (AUL… (More)
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Highly Cited
1984
Highly Cited
1984
Intensified therapy in acute lymphoblastic and acute undifferentiated leukemia in adults.
One hundred seventy adult patients with acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia (AUL) were entered… (More)
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