Activation, Metabolic

Known as: Metabolic Activation, activation metabolic, metabolic induction 
The conversion of an exogenous substance by a biological system resulting in the production on an active metabolite.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Obesity has been associated with a higher risk for impaired cognitive function, which most likely reflects associated medical… (More)
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Review
2004
Review
2004
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitously distributed environmental chemicals. PAHs acquire carcinogenicity only… (More)
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Highly Cited
2004
Highly Cited
2004
The cytochrome P450 (CYP1A1) enzyme metabolically activates many polycyclic aromatic hydrocarbons, including benzo[a]pyrene (BaP… (More)
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Highly Cited
1999
Highly Cited
1999
Cocaine cues elicit craving and physiological responses. The cerebral circuits involved in these are poorly understood. The… (More)
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Highly Cited
1999
Highly Cited
1999
In the last ten years, there has been an important increase in interest in quercetin action as a unique antioxidant, but its… (More)
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Highly Cited
1996
Highly Cited
1996
A human cytochrome P-450 (P450) 1B1 cDNA was expressed in Saccharomyces cerevisiae and the microsomes containing P450 1B1 were… (More)
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Review
1995
Review
1995
1. Development of the chemistry of polycyclic aromatic hydrocarbon (PAH) radical cations has provided evidence that these… (More)
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Highly Cited
1994
Highly Cited
1994
Clopidogrel and ticlopidine are two well known selective anti-ADP agents which are inactive in vitro and must be administered in… (More)
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Highly Cited
1993
Highly Cited
1993
A genetic polymorphism at the NAT2 gene locus, encoding for polymorphic N-acetyltransferase (NAT2), segregates individuals into… (More)
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Highly Cited
1992
Highly Cited
1992
An acetyltransferase-overexpressing strain of Salmonella typhimurium (NM2009) has been used to investigate roles of human liver… (More)
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