Acrodermatitis enteropathica

Known as: Acrodermatitis enteropathica zinc deficiency type, AEZ, ACRODERMATITIS ENTEROPATHICA, ZINC-DEFICIENCY TYPE 
An autosomal recessive genetic disorder caused by mutations in the SLC39A4 gene, encoding zinc transporter ZIP4. The condition is characterized by… (More)
National Institutes of Health

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Broader (4)

AcrodermatitisCongenital Digestive System DisorderHereditary DiseasesZinc
Autosomal recessive inheritanceCerebellar AtaxiaDiarrheaFailure to Thrive
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Papers overview

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2007
2007
Acrodermatitis enteropathica.
A 13-year-old girl presented with a history of red scaly plaques involving the chest, arms and legs beginning in infancy. Punch… (More)
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Highly Cited
2007
Highly Cited
2007
The mouse acrodermatitis enteropathica gene Slc39a4 (Zip4) is essential for early development and heterozygosity causes hypersensitivity to zinc deficiency.
The human Zip4 gene (Slc39a4) is mutated in the rare recessive genetic disorder of zinc metabolism acrodermatitis enteropathica… (More)
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2004
2004
Acrodermatitis enteropathica mutations affect transport activity, localization and zinc-responsive trafficking of the mouse ZIP4 zinc transporter.
The Zip4 protein is involved in dietary zinc uptake from the intestinal lumen. The human ZIP4 gene (SLC39A4) was identified… (More)
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Highly Cited
2003
Highly Cited
2003
The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice.
The human ZIP4 gene (SLC39A4) is a candidate for the genetic disorder of zinc metabolism acrodermatitis enteropathica. To… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of SLC39A4, a gene involved in acrodermatitis enteropathica
We have characterized the human gene SLC39A4, which encodes a protein with features characteristic of a ZIP zinc transporter. The… (More)
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Highly Cited
2001
Highly Cited
2001
Global Agro-ecological Assessment for Agriculture in the 21 st Century
This report presents a summary of the methodology and results of a comprehensive global assessment of the world’s agricultural… (More)
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Review
1996
Review
1996
Acrodermatitis enteropathica secondary to Crohn's disease.
A patient suffering from Crohn's disease (CD) presented with alopecia, eczematoid and psoriasiform lesions located on the… (More)
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Highly Cited
1993
Highly Cited
1993
Different genospecies of Borrelia burgdorferi are associated with distinct clinical manifestations of Lyme borreliosis.
Borrelia burgdorferi sensu lato has been subdivided into three genospecies: B. burgdorferi sensu stricto, B. garinii, and B… (More)
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1977
1977
Zinc correction of defective chemotaxis in acrodermatitis enteropathica.
Three patients with acrodermatitis enteropathica (AE), a disorder of zinc metabolism, demonstrated a zinc-responsive defect in… (More)
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1976
1976
Reversible intestinal mucosal abnormality in acrodermatitis enteropathica.
In 3 cases of acrodermatitis enteropathica duodenal biopsy performed at the outset of treatment showed a similar abnormality of… (More)
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