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Acetylcholinesterase Inhibitors

Known as: Acetylcholinesterase Inhibitor, Acetylcholine Hydrolase Inhibitor, AcCholE Inhibitor 
Any substance that inhibits acetylcholinesterase (AchE), an enzyme that breaks down acetylcholine (Ach) in the synaptic cleft. Inhibition of… 
National Institutes of Health

Related topics

Related topics

2 relations
Cholinesterase Inhibitor [EPC]

Broader (1)

Cholinesterase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
2006
2006
Acetylcholinesterase Inhibitors and Sleep Architecture in Patients with Alzheimer’s Disease
Background and objectiveStudies suggest that some acetylcholinesterase inhibitors (AChEIs) increase rapid eye movement (REM… 
Highly Cited
2005
Highly Cited
2005
Novel Dimeric Acetylcholinesterase Inhibitor Bis(7)-tacrine, but Not Donepezil, Prevents Glutamate-induced Neuronal Apoptosis by Blocking N-Methyl-d-aspartate Receptors*
The neuroprotective properties of bis(7)-tacrine, a novel dimeric acetylcholinesterase (AChE) inhibitor, on glutamate-induced… 
Highly Cited
2005
Highly Cited
2005
Stimulation of nicotinic acetylcholine receptors protects motor neurons.
Highly Cited
1992
Highly Cited
1992
Tacrine-induced seizures and brain damage in LiCl-treated rats can be prevented by N omega-nitro-L-arginine methyl ester.
1986
1986
Cholinergic mediation of gamma-aminobutyric acid-induced gastrin and somatostatin release from rat antrum.
Highly Cited
1985
Highly Cited
1985
Acetylcholinesterase from fetal bovine serum. Purification and characterization of soluble G4 enzyme.
1980
1980
Endogenous cholinergic modulation of growth-hormone secretion in normal and acromegalic humans.
Highly Cited
1972
Highly Cited
1972
Purification by affinity chromatography of acetylcholinesterase from electric organ tissue of the electric eel subsequent to tryptic treatment.
Highly Cited
1971
Highly Cited
1971
Relationships between the structure of organophosphorus compounds and their activity as acetylcholinesterase inhibitors.
Abstract This paper discusses the relation between chemical structure and inactivation of the enzyme acetylcholinesterase (AChE… 
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