Acetylcholinesterase Inhibitors

Known as: Acetylcholinesterase Inhibitor, Acetylcholine Hydrolase Inhibitor, AcCholE Inhibitor 
Any substance that inhibits acetylcholinesterase (AchE), an enzyme that breaks down acetylcholine (Ach) in the synaptic cleft. Inhibition of… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Alzheimer’s disease (AD) is a major form of senile dementia, characterized by progressive memory and neuronal loss combined with… (More)
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Highly Cited
2009
Highly Cited
2009
The excessive release of cytokines by the immune system contributes importantly to the pathogenesis of inflammatory diseases… (More)
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2008
2008
Increasing evidence suggests excess illness in Persian Gulf War veterans (GWV) can be explained in part by exposure of GWV to… (More)
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Highly Cited
2006
Highly Cited
2006
We investigated the anti-inflammatory effects of acetylcholinesterase inhibitors (AChEI) at the cellular and molecular levels… (More)
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2006
2006
The pathogenesis of Alzheimer's disease (AD) has been linked to a deficiency in the brain neurotransmitter acetylcholine… (More)
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Highly Cited
2004
Highly Cited
2004
Acetylcholinesterase (AChE, EC 3.1.1.7) inhibitors are the only registered drugs used to treat Alzheimer's disease (AD). New AChE… (More)
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Review
2003
Review
2003
Early diagnosis of Alzheimer's disease (AD) is needed to initiate symptomatic treatment with acetylcholinesterase inhibitors, and… (More)
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Highly Cited
2001
Highly Cited
2001
Thin-layer chromatography (TLC) was used to screen for acetylcholinesterase inhibitors from Amaryllidaceae extracts. The TLC… (More)
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Review
2000
Review
2000
A wide range of evidence shows that acetylcholinesterase (AChE) inhibitors can interfere with the progression of Alzheimer's… (More)
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Highly Cited
1996
Highly Cited
1996
Acetylcholinesterase (AChE) inhibitors from several chemical classes have been tested for the symptomatic treatment of Alzheimer… (More)
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