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Acetylcholinesterase Inhibitors
Known as:
Acetylcholinesterase Inhibitor
, Acetylcholine Hydrolase Inhibitor
, AcCholE Inhibitor
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Any substance that inhibits acetylcholinesterase (AchE), an enzyme that breaks down acetylcholine (Ach) in the synaptic cleft. Inhibition of…
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National Institutes of Health
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Related topics
Related topics
2 relations
Cholinesterase Inhibitor [EPC]
Broader (1)
Cholinesterase Inhibitors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
F. Leonetti
,
M. Catto
,
+4 authors
A. Carotti
Bioorganic & Medicinal Chemistry
2008
Corpus ID: 29259465
2006
2006
Acetylcholinesterase Inhibitors and Sleep Architecture in Patients with Alzheimer’s Disease
Jana R. Cooke
,
J. Loredo
,
+5 authors
S. Ancoli-Israel
Drugs & Aging
2006
Corpus ID: 20507460
Background and objectiveStudies suggest that some acetylcholinesterase inhibitors (AChEIs) increase rapid eye movement (REM…
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Highly Cited
2005
Highly Cited
2005
Novel Dimeric Acetylcholinesterase Inhibitor Bis(7)-tacrine, but Not Donepezil, Prevents Glutamate-induced Neuronal Apoptosis by Blocking N-Methyl-d-aspartate Receptors*
Wenming Li
,
R. Pi
,
+15 authors
Yifan Han
Journal of Biological Chemistry
2005
Corpus ID: 7778868
The neuroprotective properties of bis(7)-tacrine, a novel dimeric acetylcholinesterase (AChE) inhibitor, on glutamate-induced…
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Highly Cited
2005
Highly Cited
2005
Stimulation of nicotinic acetylcholine receptors protects motor neurons.
T. Nakamizo
,
J. Kawamata
,
+5 authors
S. Shimohama
Biochemical and Biophysical Research…
2005
Corpus ID: 37749673
Highly Cited
1992
Highly Cited
1992
Tacrine-induced seizures and brain damage in LiCl-treated rats can be prevented by N omega-nitro-L-arginine methyl ester.
G. Bagetta
,
M. Iannone
,
A. Scorsa
,
G. Nisticó
European Journal of Pharmacology
1992
Corpus ID: 36763316
1986
1986
Cholinergic mediation of gamma-aminobutyric acid-induced gastrin and somatostatin release from rat antrum.
R. Harty
,
Peggy A. Franklin
Gastroenterology
1986
Corpus ID: 23527533
Highly Cited
1985
Highly Cited
1985
Acetylcholinesterase from fetal bovine serum. Purification and characterization of soluble G4 enzyme.
J. Ralston
,
R. S. Rush
,
B. P. Doctor
,
A. D. Wolfe
Journal of Biological Chemistry
1985
Corpus ID: 23422039
1980
1980
Endogenous cholinergic modulation of growth-hormone secretion in normal and acromegalic humans.
S. A. Leveston
,
P. Cryer
Metabolism: Clinical and Experimental
1980
Corpus ID: 6316962
Highly Cited
1972
Highly Cited
1972
Purification by affinity chromatography of acetylcholinesterase from electric organ tissue of the electric eel subsequent to tryptic treatment.
Y. Dudai
,
I. Silman
,
N. Kalderon
,
S. Blumberg
Biochimica et Biophysica Acta
1972
Corpus ID: 31963720
Highly Cited
1971
Highly Cited
1971
Relationships between the structure of organophosphorus compounds and their activity as acetylcholinesterase inhibitors.
Fukuto Tr
1971
Corpus ID: 68450065
Abstract This paper discusses the relation between chemical structure and inactivation of the enzyme acetylcholinesterase (AChE…
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