Accolate
National Institutes of Health
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Zafirlukast (Accolate) {3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbo Nylaminocarbonyl)-benzyl] 1-methyl-1H-indol-5-yl}-carbamic…
26 patients with severe bronchial asthma resisitant to conventional therapy with inhlation cortikosteroids have been treated with…
5-Leukotriene pathway inhibitors, Accolate, MK-886, and Zileuton, were evaluated as chemopreventive agents in female strain A…
気管支喘息は現在，気道の慢性炎症性疾患としてとらえられており，その病態発現における種々のケミカルメディエーターの関与が明らかになっている．これらのうち，特にペプチドロイコトリエンであるLTC4，LTD4およびLTE4…
The efficacy and safety of the oral leukotriene receptor antagonist Zafirlukast ('Accolate') was assessed as maintenance therapy…
Leukotrienes have been demonstrated to play an important role as mediators of many pathophysiologic alterations of asthma…