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AZD7687

 
National Institutes of Health

Papers overview

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2019
2019
We have developed a novel mechanistic pharmacokinetic‐pharmacodynamic (PK/PD) model to describe the time course of plasma… Expand
2015
2015
Diacylglycerol O-acyltransferase 1 (DGAT1) plays an important role in synthesizing lipids, and inhibitors of DGAT1 have been… Expand
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Highly Cited
2014
Highly Cited
2014
Inhibition of diacylglycerol acyltransferase 1 (DGAT1) is a potential treatment modality for patients with type 2 diabetes… Expand
2013
2013
Inhibition of diacylglycerol acyltransferase 1 (DGAT1), which catalyses the final step in triacylglycerol (TAG) assembly, is… Expand
2013
2013
A one-week phase 1 trial with the DGAT1 inhibitor AZD7687 : lipid handling, hormone secretion and adverse effects in the gut 
2012
2012
A new series of pyrazinecarboxamide DGAT1 inhibitors was designed to address the need for a candidate drug with good potency… Expand
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