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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases.
- Bioorganic & medicinal chemistry letters
A novel, potent and selective quinazolinone series of inhibitors of p38α MAP kinase has been identified. Modifications designed… (More)
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