AZD6140

Known as: AZD 6140, AZD-6140 
 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND P2Y(12) plays an important role in regulating platelet aggregation and function. This receptor is the primary target… Expand
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2009
2009
BACKGROUND Platelet activation and thrombus renewal are keys to intraluminal thrombus formation and progression of abdominal… Expand
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Highly Cited
2009
Highly Cited
2009
PurposeTicagrelor (AZD6140) is the first reversibly binding oral P2Y12 receptor antagonist in development for reduction of… Expand
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Review
2008
Review
2008
ADP and ATP play a crucial role in platelet activation and their receptors are potential targets for antithrombotic drugs. The… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES In a substudy of DISPERSE (Dose confIrmation Study assessing anti-Platelet Effects of AZD6140 vs. clopidogRel in non… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES Our goal was to compare the safety and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate… Expand
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Review
2007
Review
2007
Clopidogrel is an effective inhibitor of platelet activation and aggregation due to its selective and irreversible blockade of… Expand
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Review
2007
Review
2007
Recent randomised studies suggest that experimental oral reversible platelet P2Y12 receptor inhibitor, AZD6140, causes dyspnoea… Expand
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Highly Cited
2006
Highly Cited
2006
AIMS This double-blind, parallel-group study was conducted to assess the pharmacodynamics, pharmacokinetics, and safety of… Expand
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