AZD2014

Known as: AZD 2014, AZD-2014 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2017
051020112017

Papers overview

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2016
2016
BACKGROUND Everolimus is a mammalian target of rapamycin (mTOR) inhibitor used in vascular endothelial growth factor (VEGF… (More)
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2016
2016
Mammalian target of rapamycin (mTOR) is a therapeutic target for head and neck squamous cell carcinoma (HNSCC). Here, we… (More)
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2015
2015
PURPOSE AZD2014 is a novel, oral, m-TORC 1/2 inhibitor that has shown in vitro and in vivo efficacy across a range of preclinical… (More)
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2015
2015
The mammalian target of rapamycin (mTOR) has emerged as a critical effector in cell growth, proliferation, survival, angiogenesis… (More)
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2015
2015
mTOR is an atypical serine threonine kinase involved in regulating major cellular functions, such as nutrients sensing, growth… (More)
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2015
2015
Mammalian target of rapamycin (mTOR) signaling is a critical pathway in the biology of acute myeloid leukemia (AML). Proviral… (More)
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2014
2014
BACKGROUND The mammalian target of rapamycin (mTOR) has been suggested as a target for radiosensitization. Given that… (More)
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2014
2014
Colorectal cancer is a major contributor of cancer-related mortality. The mammalian target or rapamycin (mTOR) signaling is… (More)
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2013
2013
The optimization of a potent and highly selective series of dual mTORC1 and mTORC2 inhibitors is described. An initial focus on… (More)
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2013
2013
Mitogen-activated protein kinase phosphatase-1 (MKP-1), also known as dual specificity phosphatase-1 (DUSP-1), plays a crucial… (More)
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