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AZD0914

Known as: ETX0914 
National Institutes of Health

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2 relations

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BarbituratesSpiro Compounds

Papers overview

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2017
2017
Effect of Susceptibility Testing Conditions on the In Vitro Antibacterial Activity of ETX0914.
2016
2016
A Phase II Trial of Single-Dose Oral ETX0914 (AZD0914) for Treatment of Uncomplicated Urogenital Gonorrhea
2016
2016
Microbiological Cure Rates and Antimicrobial Susceptibility of Neisseria gonorrhoeae to ETX0914 (AZD0914) in a Phase II Treatment Trial for Urogenital Gonorrhea
2015
2015
Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914)
ABSTRACT We tested the activity of ETX0914 against 187 Neisseria gonorrhoeae isolates from men with urethritis in Nanjing, China… 
2015
2015
In Vitro Antibacterial Activity of AZD0914 against Human Mycoplasmas and Ureaplasmas
ABSTRACT In this study, susceptibilities were determined for AZD0914, a spiropyrimidinetrione DNA gyrase inhibitor, azithromycin… 
2015
2015
Mode Of Inhibition of a novel DNA gyrase inhibitor with activity against Neisseria gonorrhoeae Inhibition of Neisseria gonorrhoeae type II Topoisomerases by the Novel Spiropyrimidinetrione AZD 0914…
We characterized the inhibition of Neisseria gonorrhoeae type II topoisomerases gyrase and topoisomerase IV by AZD0914 (Figure 1… 
2015
2015
In Vitro Activity of AZD 0914 , a Novel Bacterial DNA Gyrase / Topoisomerase IV Inhibitor , against Clinically Relevant Gram-Positive and Fastidious Gram-Negative Pathogens
AZD0914, a new spiropyrimidinetrione bacterial DNA gyrase inhibitor with a novel mode of inhibition, has activity against… 
2015
2015
In vitro susceptibility to the novel spiropyrimidinetrione antimicrobial AZD0914 among recent clinical Neisseria gonorrhoeae isolates in 20 European countries
In vitro susceptibility to the novel spiropyrimidinetrione antimicrobial AZD0914 among recent clinical Neisseria gonorrhoeae… 
2015
2015
006.2 High in vitro susceptibility to the novel spiropyrimidinetrione azd0914 among 873 contemporary clinical neisseria gonorrhoeae isolates in 21 european countries during 2012–2014
Introduction Resistance in Neisseria gonorrhoeae has emerged to all antimicrobials available for treatment of gonorrhoea. The… 
2013
2013
DNA Inhibitors again among Top New Antibacterial Prospects
Several new antimicrobial candidate drugs that share enzyme targets with fluoroquinolones but act through distinct binding sites… 
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