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AZD 1152

Known as: AZD-1152, AZD1152, Aurora kinase inhibitor AZD1152 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
A nanoparticle formulation of an Aurora B kinase inhibitor uses ion pairing to achieve controlled release and efficacious… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND To determine, for each of two dosing schedules, the dose-limiting toxicity (DLT) and maximum-tolerated dose (MTD) of… Expand
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Highly Cited
2011
Highly Cited
2011
The primary objective of this 2-part phase 1/2 study was to determine the maximum-tolerated dose (MTD) of the potent and… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS We previously identified that high Aurora B expression was associated with hepatocellular carcinoma (HCC… Expand
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Highly Cited
2009
Highly Cited
2009
BackgroundAurora B kinase is an important mitotic kinase involved in chromosome segregation and cytokinesis. It is overexpressed… Expand
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2009
2009
AZD1152, an Aurora kinase inhibitor with selectivity for Aurora B kinase, can enhance the effect of ionizing radiation (IR). The… Expand
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Highly Cited
2008
Highly Cited
2008
Overexpression of the Aurora-B kinase correlates with oncogenic transformation and poor prognosis. We evaluated the effects of… Expand
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2008
2008
M30 and M65 are ELISAs that detect different circulating forms of cytokeratin 18. Using the aurora kinase inhibitor AZD1152 and… Expand
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Highly Cited
2007
Highly Cited
2007
Purpose: In the current study, we examined the in vivo effects of AZD1152, a novel and specific inhibitor of Aurora kinase… Expand
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Highly Cited
2007
Highly Cited
2007
Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. We have recently… Expand
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