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AVE 0991

Known as: AVE0991 
National Institutes of Health

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Imidazoles

Papers overview

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2020
2020
Encapsulation of troglitazone and AVE0991 by gelation microspheres promotes epithelial transformation of adipose-derived stem cells.
2019
2019
Activation of mas restores hyperoxia-induced loss of lung epithelial barrier function through inhibition of apoptosis.
Background Neonatal therapy with a high concentration of oxygen (hyperoxia) is a known cause of bronchopulmonary dysplasia (BPD… 
2016
2016
Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats
This study investigated the acute effects of angiotensin-(1-7) and AVE0991 on active tone and vasodilator responses to bradykinin… 
2015
2015
Ang-(1-7) non-peptide mimetic (AVE0991) prevents atherogenesis in ApoE-/- mice by inhibiting perivascular macrophage infiltration and activation
2013
2013
The influence of angiotensin-(1-7) peptidomimetic (AVE 0991) and nebivolol on angiotensin I metabolism in aorta of apoE-knockout mice.
The detrimental role of over activation of renin-angiotensin system (RAS) in atherogenesis is widely recognized. Recently, we… 
2012
2012
Possible mechanism of the cardio-renal protective effects of AVE-0991, a non-peptide Mas-receptor agonist, in diabetic rats
Hypothesis: This study was designed to investigate the cardio-renal protective effect of AVE-0991, a non-peptide Mas-receptor… 
2012
2012
EFFECTION OF AVE0991 ON EXPRESSION OF MATRIX METALLOPROTEINASE-2 AND MATRIX METALLOPROTEINASE-9 IN RATS AFTER MYOCARDIAL INFARCTION
Objectives To observe the effects of nonpeptide angiotensin-(1–7) (Ang-(1–7)) analogue AVE0991 on Matrix Metalloproteinase-2 (MMP… 
2010
2010
The nonpeptide AVE0991 attenuates myocardial hypertrophy as induced by angiotensin II through downregulation of transforming growth factor-β1/Smad2 expression
The nonpeptide AVE0991 is expected to be a putative new drug for cardiovascular diseases. However, the mechanisms for the… 
2007
2007
Evidence for Mas-Mediated Bradykinin Potentiation by the Angiotensin-(1-7) Nonpeptide Mimic AVE 0991 in Normotensive Rats
We evaluated the effect of the nonpeptide mimic of angiotensin (Ang)-(1-7), AVE 0991, on the hypotensive effect of bradykinin (BK… 
2004
2004
Influence of angiotensin-(1-7)-receptor agonist AVE0991 on heart rate and blood pressure variability and baroreceptor sensitivity
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