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AVE 0118

Known as: AVE-0118, AVE0118 
National Institutes of Health

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1 relation

Broader (1)

Biphenyl Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Antiarrhythmic effect of vernakalant in electrically remodeled goat atria is caused by slowing of conduction and prolongation of postrepolarization refractoriness.
2014
2014
Homology modeling of Kv1.5 channel block by cationic and electroneutral ligands.
Review
2012
Review
2012
Altered Excitation-Contraction Coupling in Human Chronic Atrial Fibrillation.
This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic… 
Review
2009
Review
2009
Kv1.5 blockers for the treatment of atrial fibrillation: approaches to optimization of potency and selectivity and translation to in vivo pharmacology.
The treatment and prevention of atrial fibrillation (AF) remains a significant unmet medical need. Existing therapies that… 
2009
2009
Safety of the novel atrial-selective K+-channel blocker AVE0118 in experimental heart failure
Congestive heart failure (CHF) is often associated with atrial fibrillation. The safety of many antiarrhythmic drugs in CHF is… 
2008
2008
Novel Transient Outward and Ultra-rapid Delayed Rectifier Current Antagonist, AVE0118, Protects Against Ventricular Fibrillation Induced by Myocardial Ischemia
AVE0118 is a novel drug that blocks the transient outward current (Ito), the ultra rapid component of the delayed rectifier… 
2006
2006
Electrophysiological and antiarrhythmic effects of the novel antiarrhythmic agent AZD7009: a comparison with azimilide and AVE0118 in the acutely dilated right atrium of the rabbit in vitro.
AIMS To compare the electrophysiological and antiarrhythmic effects of AZD7009, azimilide, and AVE0118 in the acutely dilated… 
2006
2006
Properties of a Time-Dependent Potassium Current in Pig Atrium: Evidence for a Role of Kv1.5 in Repolarization
Cardiac electrical activity is modulated by potassium currents. Pigs have been used for antiarrhythmic drug testing, but only… 
2006
2006
FRS-070 Efficacy of "Early" Class III Drug AVE0118 on Alcohol-related Atrial Tachyarrhythmias(Clinical Arrhythmia-1 (A) FRS14,Featured Research Session,The 70th Anniversary Annual Scientific Meeting…
2005
2005
The novel Ito/IKur blocker AVE0118, but not the Ikr blocker dofetilide, restores atrial contractility after cardioversion of atrial fibrillation in the goat
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