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AURKC protein, human

Known as: ARK-3, Serine/Threonine-Protein Kinase 13, AIRK3 protein, human 
Aurora kinase C (309 aa, ~36 kDa) is encoded by the human AURKC gene. This protein is involved in protein phosphorylation that mediates centrosomal… 
National Institutes of Health

Related topics

Related topics

13 relations
AURKC geneCell Cycle ControlCytokinesisCytoskeletal Modeling

Broader (1)

aurora kinase C

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells
Mitotic centromere-associated kinesin (MCAK) is the best characterized member of the kinesin-13 family and plays important roles… 
2014
2014
Evidence toward a Dual Phosphatase Mechanism That Restricts Aurora A (Thr-295) Phosphorylation during the Early Embryonic Cell Cycle*
Background: Aurora A is a spindle-regulating mitotic kinase that has been implicated in controlling CDK1 activation. Results… 
2014
2014
Mitotic entry elucidated with bacterial toxin toolbox
The transition from G2 phase into mitosis is driven by the kinase activity of the Cdk1/cyclin B complex. Cdk1 becomes activated… 
2013
2013
Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression
BackgroundPrevious elegant studies performed in the fission yeast Schizosaccharomyces pombe have identified a requirement for… 
2011
2011
A Novel Cell-Based, High-Content Assay for Phosphorylation of Lats2 by Aurora A
Aurora A kinase is a key regulator of mitosis, which is upregulated in several human cancers, making it a potential target for… 
2009
2009
Aurora A regulates prometaphase progression by inhibiting the ability of RASSF1A to suppress APC-Cdc20 activity.
The Aurora (Ipl) kinase family plays important roles in the regulation of mitosis and tumorigenesis. The tumor suppressor RASSF1A… 
2008
2008
Phosphorylation of vimentin by Aurora A kinase: implications for the use of intermediate filaments as pharmacodynamic markers of Aurora A activity
4769 Intermediate filament proteins form extensive networks within the cytoplasm and inner nuclear membrane of vertebrate cells… 
2006
2006
IKKα Regulates the Mitotic Phase of the Cell Cycle by Modulating Aurora A Phosphorylation
The IKK complex includes two catalytic components, IKKα and IKKβ, in addition to the scaffold protein IKKγ/NEMO. Even though IKK… 
Highly Cited
2006
Highly Cited
2006
Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin.
Oncoprotein 18/Stathmin (Op18) is a microtubule-destabilizing protein that is inhibited by phosphorylation in response to many… 
Highly Cited
2003
Highly Cited
2003
A Novel Mechanism for Activation of the Protein Kinase Aurora A
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