Skip to search formSkip to main contentSkip to account menu

AURKB protein, human

Known as: Aurora- and Ipl1-like midbody-associated protein 1, aurora-related kinase 2, human, Serine/Threonine-Protein Kinase 12 Protein 
Aurora kinase B (344 aa, ~39 kDa) is encoded by the human AURKB gene. This protein plays a role in both the modulation of microtubule structure and… 
National Institutes of Health

Related topics

Related topics

16 relations
AURKB geneAURKB wt AlleleCell Cycle ControlCytokinesis

Broader (1)

Aurora Kinase B

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics
Orchestrated remodelling of the cytoskeketon is prominent during neurite extension. In contrast with the extensive… 
Highly Cited
2005
Highly Cited
2005
Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation
Aurora-B, previously known as AIM-1, is a conserved eukaryotic mitotic protein kinase. In mammals, this kinase plays an essential… 
Highly Cited
2004
Highly Cited
2004
Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression.
Megakaryocytes skip late anaphase and cytokinesis during endomitosis. We found normal expression and localization of a… 
Highly Cited
2004
Highly Cited
2004
High Expression of Aurora-B/Aurora and Ipl1-Like Midbody-Associated Protein (AIM-1) in Astrocytomas
AbstractObjective: Impaired regulation of Aurora-B/AIM-1 expression in human cells causes chromosomal abnormality and instability… 
Highly Cited
2003
Highly Cited
2003
E2F Mediates Sustained G2 Arrest and Down-regulation of Stathmin and AIM-1 Expression in Response to Genotoxic Stress*
Exposure of cells to genotoxic agents results in activation of checkpoint pathways leading to cell cycle arrest. These arrest… 
Highly Cited
2000
Highly Cited
2000
Myosin II regulatory light chain as a novel substrate for AIM-1, an aurora/Ipl1p-related kinase from rat.
Previous studies demonstrated that the phosphorylated myosin II regulatory light chain (MRLC) is localized at the cleavage furrow… 
Highly Cited
1998
Highly Cited
1998
Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells.
Aurora- and Ipl1-like midbody-associated protein (AIM-1) is a serine/ threonine kinase that is structurally related to Drosophila… 
Highly Cited
1998
Highly Cited
1998
Protein kinase profile of sperm and eggs: cloning and characterization of two novel testis-specific protein kinases (AIE1, AIE2) related to yeast and fly chromosome segregation regulators.
We have analyzed the general protein kinase expression profile in mouse sperm and eggs. A total of 41 different kinases were… 
Highly Cited
1998
Highly Cited
1998
Identification and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1
Mutations in aurora of Drosophila and related Saccharomyces cerevisiae IPL1 protein kinases are known to cause abnormal… 
Highly Cited
1997
Highly Cited
1997
Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1*
Mutations in Aurora of Drosophila and related Saccharomyces cerevisiae Ipl1 kinase are known to cause abnormal chromosome… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)