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ATF6 gene

Known as: ATF6, activating transcription factor 6 alpha, ACTIVATING TRANSCRIPTION FACTOR 6, ALPHA 
This gene plays a role in both transcriptional regulation and the unfolded protein response.
National Institutes of Health

Related topics

Related topics

6 relations
Activating Transcription Factor 6Homo sapiensStress Response SignalingTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Protective effects of a G. lucidum proteoglycan on INS-1 cells against IAPP-induced apoptosis via attenuating endoplasmic reticulum stress and modulating CHOP/JNK pathways.
2015
2015
Differential activation of ER stress pathways in myelinating cerebellar tracts
2013
2013
Implication of eIF2α kinase GCN2 in induction of apoptosis and endoplasmic reticulum stress‐responsive genes by sodium salicylate
Sodium salicylate (NaSal) can disturb cell viability by affecting the activity of multiple cellular molecules. In this work, we… 
2011
2011
Post-conditioning protecting rat cardiomyocytes from apoptosis via attenuating calcium-sensing receptor-induced endo(sarco)plasmic reticulum stress
Our previous studies demonstrated that caclium-sensing receptor (CaR) stimulation elicited phospholipase C (PLC)-mediated… 
2010
2010
Resveratrol-induced cytotoxicity in human Burkitt's lymphoma cells is coupled to the unfolded protein response
BackgroundResveratrol (RES), a natural phytoalexin found at high levels in grapes and red wine, has been shown to induce anti… 
2009
2009
The ATF6-Met[67]Val Substitution Is Associated With Increased Plasma Cholesterol Levels
Objective—Activating transcription factor 6 (ATF6) is a sensor of the endoplasmic reticulum stress response and regulates… 
Highly Cited
2007
Highly Cited
2007
Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on endoplasmic reticulum stress response gene expression and cell viability.
The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha and ATF6 beta, are cleaved during the ER stress response (ERSR… 
Highly Cited
2006
Highly Cited
2006
Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation.
Mammalian transcription factor ATF6 is constitutively synthesized as a type II transmembrane protein embedded in the endoplasmic… 
2006
2006
Analysis of ATF6 activation in Site-2 protease-deficient Chinese hamster ovary cells.
Mammalian transcription factor ATF6 is constitutively synthesized as a type II transmembrane protein embedded in the endoplasmic… 
2001
2001
Endoproteolysis of the ER Stress Transducer ATF6 in the Presence of Functionally Inactive Presenilins
Presenilin (PS) proteins facilitate endoproteolysis of selected type I transmembrane proteins such as the Alzheimer's disease (AD… 
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