ATF6 gene

Known as: ATF6, activating transcription factor 6 alpha, ACTIVATING TRANSCRIPTION FACTOR 6, ALPHA 
This gene plays a role in both transcriptional regulation and the unfolded protein response.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Eukaryotic cells cope with endoplasmic reticulum (ER) stress by activating the unfolded protein response (UPR), a coordinated… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND/AIMS We identified the glucose-regulated protein (grp) 78 as a transformation-associated gene in hepatocellular… (More)
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Highly Cited
2002
Highly Cited
2002
ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER… (More)
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Highly Cited
2002
Highly Cited
2002
All eukaryotic cells respond to the accumulation of unfolded proteins in the endoplasmic reticulum (ER) by signaling an adaptive… (More)
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Highly Cited
2002
Highly Cited
2002
ATF6 is an endoplasmic reticulum (ER) transmembrane transcription factor that is activated by the ER stress/unfolded protein… (More)
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Highly Cited
2001
Highly Cited
2001
In yeast, the transmembrane protein kinase/endoribonuclease Ire1p activated by endoplasmic reticulum stress cleaves HAC1 mRNA… (More)
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Highly Cited
2000
Highly Cited
2000
ATF6 is a membrane-bound transcription factor that activates genes in the endoplasmic reticulum (ER) stress response. When… (More)
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Highly Cited
2000
Highly Cited
2000
ATF6 is a member of the basic-leucine zipper family of transcription factors. It contains a transmembrane domain and is located… (More)
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Highly Cited
2000
Highly Cited
2000
Transcription of genes encoding molecular chaperones and folding enzymes in the endoplasmic reticulum (ER) is induced by… (More)
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Highly Cited
1999
Highly Cited
1999
The unfolded protein response (UPR) controls the levels of molecular chaperones and enzymes involved in protein folding in the… (More)
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