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ASXL2 gene
Known as:
ADDITIONAL SEX COMBS-LIKE 2
, Additional Sex Combs Like 2 (Drosophila) Gene
, ASXL2
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This gene plays a role in both chromatin modification and the positive regulation of transcription.
Topic mentions per year
Topic mentions per year
2003-2017
0
5
10
2003
2017
Related topics
Related topics
3 relations
Positive Regulation of Cell Differentiation
Transcriptional Regulation
chromatin remodeling
Related mentions per year
Related mentions per year
1968-2018
1960
1980
2000
2020
ASXL2 gene
Transcriptional Regulation
chromatin remodeling
Positive Regulation of Cell Differentiation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Treatment-free remission in chronic myeloid leukemia: floating between expectation and evidence
Michele Baccarani
Leukemia
2017
of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome…
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2016
2016
ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone methylation
U. S. Park
,
M C Kang
,
+8 authors
S-J Um
Oncogene
2016
Estrogen receptor alpha (ERα) has a pivotal role in breast carcinogenesis by associating with various cellular factors. Selective…
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2015
2015
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
Salima Daou
,
Ian Hammond-Martel
,
+12 authors
El Bachir Affar
The Journal of biological chemistry
2015
The deubiquitinase (DUB) and tumor suppressor BAP1 catalyzes ubiquitin removal from histone H2A Lys-119 and coordinates cell…
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2015
2015
ASXL2 Regulates Glucose, Lipid, and Skeletal Homeostasis.
Takashi Izawa
,
Nidhi Rohatgi
,
+8 authors
Wei Zou
Cell reports
2015
ASXL2 is an ETP family protein that interacts with PPARγ. We find that ASXL2-/- mice are insulin resistant, lipodystrophic, and…
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2014
2014
Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations.
J A Micol
,
Nicolas Duployez
,
+15 authors
Eric Jourdan
Blood
2014
Acute myeloid leukemia (AML) with t(8;21) (q22;q22) is considered to have favorable risk; however, nearly half of t(8;21…
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Highly Cited
2014
Highly Cited
2014
The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.
Robert Huether
,
Li Dong
,
+36 authors
James R. Downing
Nature communications
2014
Studies of paediatric cancers have shown a high frequency of mutation across epigenetic regulators. Here we sequence 633 genes…
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2012
2012
The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications.
Lakshminarayanan Aravind
,
Lakshminarayan M. Iyer
Cell cycle
2012
Human ASXL proteins, orthologs of Drosophila Additional Sex combs, have been implicated in conjunction with TET2 as a major…
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2012
2012
Maintenance of adult cardiac function requires the chromatin factor Asxl2.
Hsiao-Lei Lai
,
Milana Grachoff
,
+7 authors
Qiu-ling Wang
Journal of molecular and cellular cardiology
2012
During development and differentiation, cell type-specific chromatin configurations are set up to facilitate cell type-specific…
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2008
2008
Reply to “ESR1 gene amplification in breast cancer: a common phenomenon?”
Frederik Holst
,
Phillip D. Stahl
,
+10 authors
Ronald Simon
Nature Genetics
2008
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2003
2003
Identification and characterization of ASXL2 gene in silico.
Masuko Katoh
,
Masuko Katoh
International journal of oncology
2003
Drosophila Asx is a Polycomb group gene. Because Drosophila Asx mutations exhibit anterior and posterior transformations…
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