ASXL2 gene

Known as: ADDITIONAL SEX COMBS-LIKE 2, Additional Sex Combs Like 2 (Drosophila) Gene, ASXL2 
This gene plays a role in both chromatin modification and the positive regulation of transcription.

Topic mentions per year

Topic mentions per year

2003-2017
051020032017

Papers overview

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2017
2017
of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome… (More)
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2016
2016
Estrogen receptor alpha (ERα) has a pivotal role in breast carcinogenesis by associating with various cellular factors. Selective… (More)
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2015
2015
The deubiquitinase (DUB) and tumor suppressor BAP1 catalyzes ubiquitin removal from histone H2A Lys-119 and coordinates cell… (More)
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2015
2015
ASXL2 is an ETP family protein that interacts with PPARγ. We find that ASXL2-/- mice are insulin resistant, lipodystrophic, and… (More)
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2014
2014
Acute myeloid leukemia (AML) with t(8;21) (q22;q22) is considered to have favorable risk; however, nearly half of t(8;21… (More)
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Highly Cited
2014
Highly Cited
2014
Studies of paediatric cancers have shown a high frequency of mutation across epigenetic regulators. Here we sequence 633 genes… (More)
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2012
2012
Human ASXL proteins, orthologs of Drosophila Additional Sex combs, have been implicated in conjunction with TET2 as a major… (More)
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2012
2012
During development and differentiation, cell type-specific chromatin configurations are set up to facilitate cell type-specific… (More)
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2003
2003
Drosophila Asx is a Polycomb group gene. Because Drosophila Asx mutations exhibit anterior and posterior transformations… (More)
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