ASS234

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2016
02420132016

Papers overview

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2017
2017
BACKGROUND The heterogeneity of Alzheimer disease requires the development of multitarget drugs for treating the symptoms of the… (More)
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2017
2017
OBJECTIVES To evaluate the in-vitro and in-vivo effects on monoaminergic neurotransmission of ASS234, a promising multitarget… (More)
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2016
2016
HIGHLIGHTS ASS2324 is a hybrid compound resulting from the juxtaposition of donepezil and the propargylamine PF9601N ASS2324 is a… (More)
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2016
2016
Alzheimer’s disease (AD), a major neurodegenerative disorder, is a matter of health concern because of the lack of effective… (More)
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2014
2014
Monoamine oxidases (MAO) and cholinesterases are validated targets in the design of drugs for the treatment of Alzheimer's… (More)
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2014
2014
Neurodegenerative disorders are associated with different neurochemical and morphological alterations in the brain leading to… (More)
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2014
2014
On the basis of N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine (II, ASS234… (More)
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2014
2014
The design, synthesis, and biochemical evaluation of donepezil-pyridyl hybrids (DPHs) as multipotent cholinesterase (ChE) and… (More)
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2014
2014
The design, synthesis, and pharmacological evaluation of donepezil-indolyl based amines 7-10, amides 12-16, and carboxylic acid… (More)
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2013
2013
Amyloid beta (Aβ) aggregation and deposition is a key pathological hallmark of AD. Growing evidence suggests that neurotoxicity… (More)
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