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ASPARAGINASE

Known as: Lcf-ASP, Deaminase, Asparagine, ASP-1 
An enzyme isolated from the bacterium Escherichia coli or the bacterium Erwinia carotovora with antileukemic activity. Asparaginase hydrolyzes L… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (17)

AIEOP protocol 8202Asparaginase medacAsrgl1 protein, ratCrasnitin

Broader (2)

AmidohydrolasesAntineoplastic Agents
AspartateCOPAD protocolErwinia asparaginase 10000 UNT InjectionIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model
Osteonecrosis is a common dose-limiting toxicity of glucocorticoids. Data from clinical trials suggest that other medications can… 
Highly Cited
2009
Highly Cited
2009
Modified cyclodextrins for fast and sensitive chiral‐capillary electrophoresis‐mass spectrometry
In this work, three modified CDs (mCDs), namely 6‐deoxy‐6‐[1‐(2‐amino)ethylamino]‐β‐CD, 6‐deoxy‐6‐[N‐(2‐methylamino)pyridine… 
Review
1999
Review
1999
Bioconjugation in pharmaceutical chemistry.
Highly Cited
1993
Highly Cited
1993
In vitro and in vivo studies with a series of hexapeptide endothelin antagonists.
The effects of different amino acids incorporated into the 16 and 17 positions of the C-terminal hexapeptide of ET-1 were… 
Highly Cited
1991
Highly Cited
1991
Glycosaparaginase from human leukocytes. Inactivation and covalent modification with diazo-oxonorvaline.
Highly Cited
1983
Highly Cited
1983
Stimulation of GABA release from retinal horizontal cells by potassium and acidic amino acid agonists
Highly Cited
1983
Highly Cited
1983
Kainate‐Enhanced Release of d‐[3H]Aspartate from Cerebral Cortex and Striatum: Reversal by Baclofen and Pentobarbital
A study was made of the actions of the excitant neurotoxin, kainic acid, on the uptake and the release of d‐[2,3‐3H]aspartate (d… 
Highly Cited
1973
Highly Cited
1973
The occurrence of N‐acetylaspartate amidohydrolase (Aminoacylase II) in the developing rat 1
Of The amino acids and derivatives, N‐acetyl‐L‐aspartic acid is present in a uniquely high level (5–6 μmol/g) in the brain of… 
Highly Cited
1966
Highly Cited
1966
Degradation of allantoin by Pseudomonas acidovorans.
Highly Cited
1952
Highly Cited
1952
Transamination and associated deamidation of asparagine and glutamine.
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