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AS1411
Known as:
AS 1411
, AS-1411
, Anti-Nucleolin Aptamer AS1411
A 26-base guanine-rich oligodeoxynucleotide aptamer with potential apoptotic induction activity. Upon administration, anti-nucleolin aptamer AS1411…
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National Institutes of Health
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AGRO 100
NCIt Antineoplastic Agent Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Label-free electrochemical aptasensor constructed by layer-by-layer technology for sensitive and selective detection of cancer cells.
Tianshu Wang
,
Jiyang Liu
,
Xiaoxiao Gu
,
Dan Li
,
Jin Wang
,
E. Wang
Analytica Chimica Acta
2015
Corpus ID: 35746419
2015
2015
Tumor targeting with a 99mTc-labeled AS1411 aptamer in prostate tumor cells
Zohreh Noaparast
,
S. Hosseinimehr
,
Majid Piramoon
,
S. M. Abedi
Journal of drug targeting (Print)
2015
Corpus ID: 38490268
Abstract AS1411, a 26-base guanine-rich oligonucleotide aptamer, has high affinity to nucleolin, mainly on tumor cell surfaces…
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2015
2015
Synthesis of fluorescent dye-doped silica nanoparticles for target-cell-specific delivery and intracellular microRNA imaging.
Henan Li
,
Yawen Mu
,
+4 authors
Songqin Liu
In Analysis
2015
Corpus ID: 2783290
MicroRNA (miRNA) is found to be up-regulated in many kinds of cancer and therefore is classified as an oncomiR. Herein, we design…
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2015
2015
Visual detection of mercury(II) based on recognition of the G-quadruplex conformational transition by a cyanine dye supramolecule.
Hongbo Chen
,
Xiu-feng Zhang
,
+4 authors
Yalin Tang
In Analysis
2015
Corpus ID: 34691938
A supramolecular probe for visual detection of mercury (Hg) has been designed by using a cyanine dye and AS1411 G-quadruplexes…
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2015
2015
Study of the Function of G-Rich Aptamers Selected for Lung Adenocarcinoma.
Jun Hu
,
Zilong Zhao
,
+4 authors
W. Tan
Chemistry - An Asian Journal
2015
Corpus ID: 19228853
Guanine (G)-rich oligonucleotides have attracted considerable interest as therapeutic agents. Two G-rich aptamers were selected…
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2011
2011
Simple PEG Modification of DNA Aptamer Based on Copper Ion Coordination for Tumor Targeting
Yoshimasa Takafuji
,
J. Jo
,
Y. Tabata
Journal of Biomaterials Science. Polymer Edition
2011
Corpus ID: 25484781
A simple modification of a DNA aptamer with poly(ethylene glycol) (PEG) based on metal coordination was developed. N,N-bis…
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2009
2009
PRMT 5 , a Novel TRAIL Receptor-Binding Protein , Inhibits TRAIL-Induced Apoptosis via Nuclear Factor-κ B Activation
Hiroshi Tanaka
,
Y. Hoshikawa
,
+6 authors
N. Fujita
2009
Corpus ID: 42011775
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and has selective…
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2009
2009
G-rich oligonucleotides for cancer treatment.
P. Bates
,
E. Choi
,
L. Nayak
Methods in molecular biology
2009
Corpus ID: 39015778
Oligonucleotides with guanosine-rich (G-rich) sequences often have unusual physical and biological properties, including…
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2007
2007
Activity and Mechanism of Action of AS1411 in Acute Myeloid Leukemia Cells.
Weiwei Chen
,
V. Sridharan
,
+4 authors
D. Fernandes
2007
Corpus ID: 89238364
AS1411 is a 26 base unmodified DNA aptamer which is currently in a Phase II clinical trial for the treatment of acute myeloid…
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2006
2006
A role for protein arginine methyltransferase 5 (PRMT5) in the mechanism of novel anticancer agent, AS1411.
Y. Teng
,
P. Bates
2006
Corpus ID: 83100773
Proc Amer Assoc Cancer Res, Volume 47, 2006 5507 AS1411 (formerly AGRO100) is a guanosine-rich phosphodiester…
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