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ARNT protein, human

Known as: Hypoxia-Inducible Factor 1 Beta, melanoma inhibitory activity 3, human, Dioxin Receptor, Nuclear Translocator 
Aryl hydrocarbon receptor nuclear translocator (789 aa, ~87 kDa) is encoded by the human ARNT gene. This protein plays a role in transcriptional… 
National Institutes of Health

Related topics

Related topics

20 relations
AHR Signal Transduction PathwayARNT geneARNT wt AlleleAngiogenesis Pathway

Broader (1)

Aryl Hydrocarbon Receptor Nuclear Translocator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Understanding dioxin developmental toxicity using the zebrafish model.
Zebrafish (Danio rerio) have advantages over mammals as an animal model for investigating developmental toxicity. 2,3,7,8… 
Highly Cited
2005
Highly Cited
2005
ERα-AHR-ARNT Protein-Protein Interactions Mediate Estradiol-dependent Transrepression of Dioxin-inducible Gene Transcription*
The aryl hydrocarbon receptor (AHR) and the aryl hydrocarbon receptor nuclear translocator (ARNT) form a heterodimeric… 
Highly Cited
2005
Highly Cited
2005
Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression.
Hypoxia-inducible factor (HIF)-deficient placentas exhibit a number of defects, including changes in cell fate adoption, lack of… 
Highly Cited
2002
Highly Cited
2002
Identification of Functional Hypoxia Response Elements in the Promoter Region of the DEC1 and DEC2 Genes*
Adaptation to hypoxia is a crucial process both physiologically (i.e. in chondrocytes) and pathologically (i.e. in tumor cells… 
Highly Cited
2000
Highly Cited
2000
Role of hypoxia‐inducible factor‐1 in hypoxia‐induced ischemic tolerance in neonatal rat brain
Hypoxia‐inducible factor‐1 (HIF‐1) is a heterodimer composed of HIF‐1α and HIF‐1β protein subunits. This transcription factor is… 
Review
1997
Review
1997
Aryl hydrocarbon receptor-mediated signal transduction.
The aryl hydrocarbon (or dioxin) receptor (AhR) is a ligand-activated basic helix-loop-helix (bHLH) protein that heterodimerizes… 
Highly Cited
1996
Highly Cited
1996
The Role of the Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) in Hypoxic Induction of Gene Expression
Hypoxia-inducible factor-1 (HIF-1), a DNA-binding complex implicated in the regulation of gene expression by oxygen, has been… 
Highly Cited
1995
Highly Cited
1995
Protein‐protein interaction via PAS domains: role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor‐Arnt transcription factor complex.
Gene regulation by dioxins is mediated by the dioxin receptor‐Arnt heterodimer, a ligand generated complex of two basic helix… 
Highly Cited
1994
Highly Cited
1994
Tissue specific expression of the rat Ah-receptor and ARNT mRNAs.
The Ah-receptor (AHR) is a ligand activated transcription factor that mediates the biological effects of agonists such as 2,3,7,8… 
Highly Cited
1992
Highly Cited
1992
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.
A cDNA encoding the murine Ah receptor (Ahb-1 allele for aromatic hydrocarbon responsiveness) has been isolated and characterized… 
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