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ARHGAP18 gene

Known as: ARHGAP18, MacGAP, Rho GTPase activating protein 18 
National Institutes of Health

Related topics

Related topics

1 relation
ARHGAP15 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis
Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic… 
Highly Cited
2017
Highly Cited
2017
ARHGAP18 Downregulation by miR-200b Suppresses Metastasis of Triple-Negative Breast Cancer by Enhancing Activation of RhoA.
Rho GTPases activated in cancer cells drive proliferation, migration, and metastasis. Thus, RhoGAP proteins, which negatively… 
2017
2017
The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells
Localization of a regulator of RhoGTPases (ARHGAP18) is important for microtubule stability and endothelial cell function. The… 
2017
2017
ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype
Rationale: Thoracic aortic aneurysm (TAA) is a potentially lethal condition, which can affect individuals of all ages. TAA may be… 
2015
2015
Caveolae control the anti-inflammatory phenotype of senescent endothelial cells
Senescent endothelial cells (EC) have been identified in cardiovascular disease, in angiogenic tumour associated vessels and in… 
2014
2014
ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions
The formation of the vascular network requires a tightly controlled balance of pro-angiogenic and stabilizing signals… 
Highly Cited
2011
Highly Cited
2011
ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility
Using a library of siRNAs, we found that ARHGAP18 was essential for the organization of actin stress fibers and focal adhesion… 
2011
2011
Novel Common Integration Sites Targeted by Mouse Mammary Tumor Virus Insertion in Mammary Tumors Have Oncogenic Activity
Non-acute transforming retroviruses like mouse mammary tumor virus (MMTV) cause cancer, at least in part, through integration… 
Highly Cited
2009
Highly Cited
2009
Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia
We have discovered two genes, RSRC1 and ARHGAP18, associated with schizophrenia and in an independent study provided additional… 
2008
2008
New member of the guanosine triphosphatase activating protein family in the human epididymis.
The effect of the guanosine triphosphatase activating proteins (GAPs) on spermatogenesis has been studied for years, though no… 
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