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ARHGAP18 gene
Known as:
ARHGAP18
, MacGAP
, Rho GTPase activating protein 18
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National Institutes of Health
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Related topics
Related topics
1 relation
ARHGAP15 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis
A. Lay
,
Paul R. Coleman
,
+6 authors
J. Gamble
Journal of the American Heart Association
2019
Corpus ID: 58553864
Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic…
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Highly Cited
2017
Highly Cited
2017
ARHGAP18 Downregulation by miR-200b Suppresses Metastasis of Triple-Negative Breast Cancer by Enhancing Activation of RhoA.
Brock A. Humphries
,
Zhishan Wang
,
Yunfei Li
,
Jing-Ru Jhan
,
Yiguo Jiang
,
Chengfeng Yang
Cancer research
2017
Corpus ID: 4768418
Rho GTPases activated in cancer cells drive proliferation, migration, and metastasis. Thus, RhoGAP proteins, which negatively…
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2017
2017
The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells
M. Lovelace
,
Elizabeth E Powter
,
+12 authors
J. Gamble
Molecular biology of the cell
2017
Corpus ID: 6858409
Localization of a regulator of RhoGTPases (ARHGAP18) is important for microtubule stability and endothelial cell function. The…
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2017
2017
ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype
Renjing Liu
,
L. Lo
,
+13 authors
J. Gamble
Circulation research
2017
Corpus ID: 38693846
Rationale: Thoracic aortic aneurysm (TAA) is a potentially lethal condition, which can affect individuals of all ages. TAA may be…
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2015
2015
Caveolae control the anti-inflammatory phenotype of senescent endothelial cells
Elizabeth E Powter
,
Paul R. Coleman
,
+5 authors
J. Gamble
Aging cell
2015
Corpus ID: 18216737
Senescent endothelial cells (EC) have been identified in cardiovascular disease, in angiogenic tumour associated vessels and in…
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2014
2014
ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions
Garry Chang
,
A. Lay
,
+11 authors
J. Gamble
Small GTPases
2014
Corpus ID: 34675165
The formation of the vascular network requires a tightly controlled balance of pro-angiogenic and stabilizing signals…
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Highly Cited
2011
Highly Cited
2011
ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility
Masao Maeda
,
H. Hasegawa
,
+8 authors
T. Senga
Molecular biology of the cell
2011
Corpus ID: 644554
Using a library of siRNAs, we found that ARHGAP18 was essential for the organization of actin stress fibers and focal adhesion…
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2011
2011
Novel Common Integration Sites Targeted by Mouse Mammary Tumor Virus Insertion in Mammary Tumors Have Oncogenic Activity
Hyoung Kim
,
A. V. D. van den Heuvel
,
John W. Schmidt
,
S. Ross
PloS one
2011
Corpus ID: 17307613
Non-acute transforming retroviruses like mouse mammary tumor virus (MMTV) cause cancer, at least in part, through integration…
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Highly Cited
2009
Highly Cited
2009
Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia
S. Potkin
,
J. Turner
,
+4 authors
F. Macciardi
Molecular Psychiatry
2009
Corpus ID: 22985140
We have discovered two genes, RSRC1 and ARHGAP18, associated with schizophrenia and in an independent study provided additional…
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2008
2008
New member of the guanosine triphosphatase activating protein family in the human epididymis.
Xiangqi Li
,
Qiang Liu
,
Shigui Liu
,
Jinsong Zhang
,
Yonglian Zhang
Acta biochimica et biophysica Sinica
2008
Corpus ID: 32942569
The effect of the guanosine triphosphatase activating proteins (GAPs) on spermatogenesis has been studied for years, though no…
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