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ARGININOSUCCINATE LYASE

Known as: Argininosuccinase, Argininosuccinate Lyase [Chemical/Ingredient], N-(L-Argininosuccinate) arginine-lyase 
An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC… Expand
National Institutes of Health

Related topics

Related topics

13 relations
ASL geneArgininosuccinate lyase:CCnt:Pt:CVS:QnArgininosuccinate lyase:CCnt:Pt:Liver^fetus:QnArgininosuccinate lyase:CCnt:Pt:RBC:Qn
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Broader (1)

Amidine-Lyases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma
Arginine deprivation, either by nutritional starvation or exposure to ADI-PEG20, induces adaptive transcriptional upregulation of… Expand
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Highly Cited
2011
Highly Cited
2011
Requirement of argininosuccinate lyase for systemic nitric oxide production
Nitric oxide (NO) is crucial in diverse physiological and pathological processes. We show that a hypomorphic mouse model of… Expand
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Highly Cited
2010
Highly Cited
2010
Regulation of Cellular Metabolism by Protein Lysine Acetylation
Metabolic Regulation Through Acetylation Covalent modification of lysine residues in various proteins in the nucleus is a… Expand
Highly Cited
2001
Highly Cited
2001
Tandem mass spectrometric analysis for amino, organic, and fatty acid disorders in newborn dried blood spots: a two-year summary from the New England Newborn Screening Program.
BACKGROUND Tandem mass spectrometry (MS/MS) is rapidly being adopted by newborn screening programs to screen dried blood spots… Expand
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Highly Cited
1996
Highly Cited
1996
Coinduction of Nitric Oxide Synthase, Argininosuccinate Synthetase, and Argininosuccinate Lyase in Lipopolysaccharide-treated Rats
Nitric oxide (NO) is synthesized from arginine by nitric oxide synthase (NOS), and citrulline which is generated can be recycled… Expand
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Highly Cited
1989
Highly Cited
1989
The argininosuccinate lyase gene of Chlamydomonas reinhardtii: an important tool for nuclear transformation and for correlating the genetic and molecular maps of the ARG7 locus.
The argininosuccinate lyase (ASL) gene of Chlamydomonas reinhardtii has been cloned using four oligonucleotide probes… Expand
Highly Cited
1988
Highly Cited
1988
Gene sharing by delta-crystallin and argininosuccinate lyase.
The lens structural protein delta-crystallin and the metabolic enzyme argininosuccinate lyase (ASL; L-argininosuccinate arginine… Expand
Review
1986
Review
1986
Biosynthesis and metabolism of arginine in bacteria.
INTRODUCTION ...................................................... 315 BIOSYNTHESIS OF ARGININE… Expand
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Highly Cited
1978
Highly Cited
1978
Functional expression of cloned yeast DNA in Escherichia coli: specific complementation of argininosuccinate lyase (argH) mutations.
Abstract Segments of yeast ( Saccharomyces cerevisiae ) DNA cloned on various plasmid vectors in Escherichia coli can be… Expand
Highly Cited
1963
Highly Cited
1963
Studies on factors affecting the levels of urea cycle enzymes in rat liver.
  • R. Schimke
  • The Journal of biological chemistry
  • 1963
    • Corpus ID: 6182801
It has been previously demonstrated that the hepatic level of each enzyme concerned with the biosynthesis of urea in the rat, i.e… Expand
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