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ARGININOSUCCINATE LYASE

Known as: Argininosuccinase, Argininosuccinate Lyase [Chemical/Ingredient], N-(L-Argininosuccinate) arginine-lyase 
An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC… 
National Institutes of Health

Related topics

Related topics

13 relations
ASL geneArgininosuccinate lyase:CCnt:Pt:CVS:QnArgininosuccinate lyase:CCnt:Pt:Liver^fetus:QnArgininosuccinate lyase:CCnt:Pt:RBC:Qn

Broader (1)

Amidine-Lyases

Papers overview

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Highly Cited
1995
Highly Cited
1995
Recycling of l-citrulline to sustain nitric oxide-dependent enteric neurotransmission
Highly Cited
1984
Highly Cited
1984
The nucleotide sequence of the yeast ARG4 gene.
1981
1981
Argininosuccinate lyase: purification and characterization from human liver.
Argininosuccinate lyase has been purified to near homogeneity and partially characterized from extracts of human liver. The… 
1977
1977
Urea as a selective inhibitor of argininosuccinate lyase.
The effect of urea on various ornithine cycle enzymes has been investigated. It was demonstrated that argininosuccinate lyase was… 
Highly Cited
1972
Highly Cited
1972
Control of arginine biosynthesis in Pseudomonas aeruginosa.
SUMMARY: Arginine biosynthesis in Pseudomonas aeruginosa proceeded via transacetylation of acetylornithine with glutamate; it… 
1970
1970
Biosynthesis of urea. 8. Dissociation-association kinetics and equilibria of argininosuccinase.
Abstract Further study of the cold inactivation of argininosuccinase shows that a new, more slowly sedimenting component is… 
Highly Cited
1968
Highly Cited
1968
DEVELOPMENT OF UREA‐SYNTHESIZING ENZYMES IN HUMAN LIVER
Liver slices from human foetuses of a gestational age between 16 and 20 weeks produce urea when incubated with optimal amounts of… 
Highly Cited
1968
Highly Cited
1968
Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli. 3. Repression of enzymes of arginine biosynthesis in arginyl-tRNA synthetase mutants.
1967
1967
Variation of the enzymes of the urea cycle and aspartate transcarbamylase in liver of pregnant rats.
The variations in the specific activities of the enzymes of the urea cycle were studied in the livers of pregnant rats and also… 
Highly Cited
1964
Highly Cited
1964
ENZYMES OF ARGININE METABOLISM IN MAMMALIAN CELL CULTURE. I. REPRESSION OF ARGININOSUCCINATE SYNTHETASE AND ARGININOSUCCINASE.
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