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ARGININOSUCCINATE LYASE

Known as: Argininosuccinase, Argininosuccinate Lyase [Chemical/Ingredient], N-(L-Argininosuccinate) arginine-lyase 
An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC… 
National Institutes of Health

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Related topics

13 relations
ASL geneArgininosuccinate lyase:CCnt:Pt:CVS:QnArgininosuccinate lyase:CCnt:Pt:Liver^fetus:QnArgininosuccinate lyase:CCnt:Pt:RBC:Qn
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Broader (1)

Amidine-Lyases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma
Arginine deprivation, either by nutritional starvation or exposure to ADI-PEG20, induces adaptive transcriptional upregulation of… 
Highly Cited
2011
Highly Cited
2011
Requirement of argininosuccinate lyase for systemic nitric oxide production
Nitric oxide (NO) is crucial in diverse physiological and pathological processes. We show that a hypomorphic mouse model of… 
Highly Cited
2010
Highly Cited
2010
Regulation of Cellular Metabolism by Protein Lysine Acetylation
Metabolic Regulation Through Acetylation Covalent modification of lysine residues in various proteins in the nucleus is a… 
Highly Cited
2001
Highly Cited
2001
Tandem mass spectrometric analysis for amino, organic, and fatty acid disorders in newborn dried blood spots: a two-year summary from the New England Newborn Screening Program.
BACKGROUND Tandem mass spectrometry (MS/MS) is rapidly being adopted by newborn screening programs to screen dried blood spots… 
Review
2001
Review
2001
Arginine metabolism and the synthesis of nitric oxide in the nervous system
Highly Cited
1996
Highly Cited
1996
Coinduction of Nitric Oxide Synthase, Argininosuccinate Synthetase, and Argininosuccinate Lyase in Lipopolysaccharide-treated Rats
Nitric oxide (NO) is synthesized from arginine by nitric oxide synthase (NOS), and citrulline which is generated can be recycled… 
Highly Cited
1989
Highly Cited
1989
The argininosuccinate lyase gene of Chlamydomonas reinhardtii: an important tool for nuclear transformation and for correlating the genetic and molecular maps of the ARG7 locus.
The argininosuccinate lyase (ASL) gene of Chlamydomonas reinhardtii has been cloned using four oligonucleotide probes… 
Highly Cited
1988
Highly Cited
1988
Gene sharing by delta-crystallin and argininosuccinate lyase.
The lens structural protein delta-crystallin and the metabolic enzyme argininosuccinate lyase (ASL; L-argininosuccinate arginine… 
Highly Cited
1986
Highly Cited
1986
Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid.
Highly Cited
1963
Highly Cited
1963
Studies on factors affecting the levels of urea cycle enzymes in rat liver.
  • R. Schimke
  • The Journal of biological chemistry
  • 1963
  • Corpus ID: 6182801
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