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ARG2 gene

Known as: ARG2, ARGINASE 2 
 
National Institutes of Health

Related topics

Related topics

1 relation
arginase II, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma.
Neuroblastoma is the most common childhood solid tumor, yet the prognosis for high-risk disease remains poor. We demonstrate here… Expand
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2018
2018
Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2
Our previous studies have implicated expression of the mitochondrial isoform of the arginase enzyme arginase 2 (A2) in… Expand
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2017
2017
Arginine metabolic endotypes related to asthma severity
Aims Arginine metabolism via inducible nitric oxide synthase (iNOS) and arginase 2 (ARG2) is higher in asthmatics than in healthy… Expand
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2016
2016
Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury
Retinal ischemia is a major cause of visual impairment and blindness and is involved in various disorders including diabetic… Expand
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2015
2015
Arginase 2 deficiency results in spontaneous steatohepatitis: a novel link between innate immune activation and hepatic de novo lipogenesis.
BACKGROUND & AIMS Innate immune activation has been postulated as a central mechanism for disease progression from hepatic… Expand
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2014
2014
ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis
Impaired autophagy function and enhanced ARG2 (arginase 2)-MTOR (mechanistic target of rapamycin) crosstalk are implicated in… Expand
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2014
2014
Glucocorticoids induce gastroparesis in mice through depletion of l-arginine.
Glucocorticoids (GCs) constitute a highly pleiotropic class of drugs predominantly employed in the treatment of inflammatory… Expand
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2014
2014
OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase.
RATIONALE Increased arginase activity contributes to endothelial dysfunction by competition for l-arginine substrate and… Expand
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2013
2013
IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.
Although previous literature suggests that interleukin (IL)-13, a T-helper type 2 cell effector cytokine, might be involved in… Expand
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2011
2011
Arginase 2 Deletion Reduces Neuro-Glial Injury and Improves Retinal Function in a Model of Retinopathy of Prematurity
Background Retinopathy of prematurity (ROP) is a major cause of vision impairment in low birth weight infants. While previous… Expand
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