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AR C124910XX

Known as: AR-C124910XX 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Adenosine
analogs & derivatives

Papers overview

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2019
2019
Simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX, in human plasma by liquid chromatography-tandem mass spectrometry: Applications in steady-state pharmacokinetics in…
A sensitive and simple liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous… 
2018
2018
Effects of food and gender on pharmacokinetics of ticagrelor and its main active metabolite AR-C124910XX in healthy Chinese subjects
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OBJECTIVES The manuscript was mainly aimed to evaluate effects of food and gender on the pharmacokinetics of ticagrelor and its… 
2016
2016
Which platelet function test best reflects the in vivo plasma concentrations of ticagrelor and its active metabolite?
Summary Aim of this study was assessment of the relationship between concentrations of ticagrelor and its active metabolite (AR… 
2015
2015
Does morphine administration affect ticagrelor conversion to its active metabolite in patients with acute myocardial infarction? A sub-analysis of the randomized, double-blind, placebo- -controlled…
Background. Therapy with aspirin and one of the platelet P2Y12 receptor inhibitors, preferably ticagrelor or prasugrel, is the… 
2015
2015
Pharmacokinetics and pharmacodynamics of ticagrelor and prasugrel in healthy male Korean volunteers.
2013
2013
Evaluation of the pharmacokinetic interaction between ticagrelor and tolbutamide, a cytochrome P450 2C9 substrate, in healthy volunteers.
OBJECTIVES To assess the effect of ticagrelor on the pharmacokinetics of tolbutamide (a CYP2C9 substrate), and the effect of… 
2012
2012
Effect of age and gender on pharmacokinetics and pharmacodynamics of a single ticagrelor dose in healthy individuals
The aim of this study was to assess age and gender effects on ticagrelor pharmacokinetics and pharmacodynamics (PK/PD). Forty… 
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