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AR C124910XX

Known as: AR-C124910XX 
 
National Institutes of Health

Papers overview

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2016
2016
BACKGROUND The PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients with Prior Heart Attack Using Ticagrelor Compared… Expand
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2015
2015
Background. Therapy with aspirin and one of the platelet P2Y12 receptor inhibitors, preferably ticagrelor or prasugrel, is the… Expand
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2015
2015
OBJECTIVES The goal of this study was to assess the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of escalating… Expand
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2015
2015
ObjectiveThe objective of this study was to assess the pharmacokinetic and pharmacodynamic behavior of ticagrelor administered… Expand
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2012
2012
PurposeTicagrelor, a reversibly binding oral P2Y12 receptor antagonist, is predominantly metabolized by cytochrome P450 3A and… Expand
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2011
2011
Ticagrelor is the first direct acting reversibly binding oral platelet P2Y(12) receptor antagonist. The parent molecule and the… Expand
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2011
2011
Ticagrelor, a P2Y₁₂ receptor antagonist that inhibits ADP-induced platelet aggregation (IPA), has demonstrated improved outcomes… Expand
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Highly Cited
2010
Highly Cited
2010
Ticagrelor [(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl) cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d… Expand
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Highly Cited
2010
Highly Cited
2010
Rapid and sensitive analytical methods using liquid chromatography with tandem mass spectrometry (LC/MS/MS) were developed for… Expand
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Highly Cited
2009
Highly Cited
2009
PurposeTicagrelor (AZD6140) is the first reversibly binding oral P2Y12 receptor antagonist in development for reduction of… Expand
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