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APPL2 gene

Known as: DCC-interacting protein 13-beta, ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN, AND LEUCINE ZIPPER-CONTAINING PROTEIN 2, DIP13-BETA 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Adiponectin-Resistance in Obesity.
  • A. Engin
  • Advances in Experimental Medicine and Biology
  • 2017
  • Corpus ID: 13335953
The decrease in adiponectin levels are negatively correlated with chronic subclinical inflammation markers in obesity. The… 
Review
2017
Review
2017
APPLs: More than just adiponectin receptor binding proteins.
2015
2015
Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages
Rab31 recruits APPL2 to regulate phagocytic cup closure and FcγR signaling pathways via production of PI(3,4,5)P3 in macrophages… 
Highly Cited
2009
Highly Cited
2009
Yin-Yang Regulation of Adiponectin Signaling by APPL Isoforms in Muscle Cells*
APPL1 is a newly identified adiponectin receptor-binding protein that positively mediates adiponectin signaling in cells. Here we… 
Highly Cited
2009
Highly Cited
2009
Endosomal Adaptor Proteins APPL1 and APPL2 Are Novel Activators of β-Catenin/TCF-mediated Transcription*
Canonical Wnt signaling regulates many aspects of cellular physiology and tissue homeostasis during development and in adult… 
Highly Cited
2009
Highly Cited
2009
Appl1 Is Dispensable for Mouse Development, and Loss of Appl1 Has Growth Factor-selective Effects on Akt Signaling in Murine Embryonic Fibroblasts*
The adaptor protein APPL1 (adaptor protein containing pleckstrin homology (PH), phosphotyrosine binding (PTB), and leucine zipper… 
Highly Cited
2007
Highly Cited
2007
APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex
2007
2007
Membrane Targeting by APPL1 and APPL2: Dynamic Scaffolds that Oligomerize and Bind Phosphoinositides
Human adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (APPL1) and adaptor protein… 
Highly Cited
2004
Highly Cited
2004
APPL Proteins Link Rab5 to Nuclear Signal Transduction via an Endosomal Compartment
Review
2004
Review
2004
Endocytosis: Signaling from Endocytic Membranes to the Nucleus
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