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Olfactory dysfunction is often accompanied with anxiety- and depressive-like behaviors in depressive patients. Impaired… Expand The decrease in adiponectin levels are negatively correlated with chronic subclinical inflammation markers in obesity. The… Expand Rab31 recruits APPL2 to regulate phagocytic cup closure and FcγR signaling pathways via production of PI(3,4,5)P3 in macrophages… Expand APPL1 is a newly identified adiponectin receptor-binding protein that positively mediates adiponectin signaling in cells. Here we… Expand Canonical Wnt signaling regulates many aspects of cellular physiology and tissue homeostasis during development and in adult… Expand The adaptor protein APPL1 (adaptor protein containing pleckstrin homology (PH), phosphotyrosine binding (PTB), and leucine zipper… Expand Human adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (APPL1) and adaptor protein… Expand A number of signaling proteins have been demonstrated to interact with follicle stimulating hormone (FSH) receptor (FSHR… Expand Signals generated in response to extracellular stimuli at the plasma membrane are transmitted through cytoplasmic transduction… Expand Abstract Recent studies have indicated that some endocytic proteins are also involved in direct signaling pathways from membranes… Expand