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Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues
HOTAIR is a known long non-coding RNA which has recently been associated with the progression of some cancer types. It has been reported that HOTAIR expression is correlated with SUZ12 expressionExpand
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In vitro Cytotoxic and Antimicrobial Activity of Essential Oil From Satureja Intermedia
Background Many members of the genus Satureja have aromatic and medicinal characteristics. Objectives Objectives The purpose of the present work was to determine cytotoxic activity of the essentialExpand
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Inhibition of the mevalonate pathway enhances carvacrol biosynthesis and DXR gene expression in shoot cultures of Satureja khuzistanica Jamzad.
Carvacrol is a major component of Satureja khuzistanica Jamzad (≤90%) that has significant antimicrobial and antioxidant properties. Considering the specific capabilities of S. khuzistanica toExpand
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Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect.
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linkedExpand
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Salicylic acid improves podophyllotoxin production in cell cultures of Linum album by increasing the expression of genes related with its biosynthesis
Treatment of Linum album cell cultures with 10 μM salicylic acid (SA) for 3 days improved podophyllotoxin (PTOX) production up to 333 μg/g dry weight (DW): over three times that of the controlExpand
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Podophyllotoxin: Current approaches to its biotechnological production and future challenges
Many plant‐derived agents are being used to treat cancer, including taxol, vinblastine, vincristine, or camptothecin and podophyllotoxin derivatives, among others. Plant biotechnology can provide aExpand
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The effect of light on gene expression and podophyllotoxin biosynthesis in Linum album cell culture.
Podophyllotoxin (PTOX) is a naturally occurring phenolic compound isolated as an active anti-tumor agent. The stimulatory influence of light on the formation of phenolic compounds has been reported,Expand
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NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals
Mammalian inosine triphosphatase encoded by ITPA gene hydrolyzes ITP and dITP to monophosphates, avoiding their deleterious effects. Itpa− mice exhibited perinatal lethality, and significantly higherExpand
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ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.
Inosine triphosphate pyrophosphatase (ITPA protein) (EC 3.6.1.19) hydrolyzes deaminated purine nucleoside triphosphates, such as ITP and dITP, to their corresponding purine nucleoside monophosphateExpand
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Ultrasound-potentiated salicylic acid-induced physiological effects and production of taxol in hazelnut (Corylus avellana L.) cell culture.
Effects of ultrasound (US), salicylic acid (SA) and their combined use on the growth and secondary metabolite production of suspension-cultured Corylus avellana cells were investigated. The culturesExpand
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