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APH1A gene

Known as: APH-1A, ANTERIOR PHARYNX DEFECTIVE 1, C. ELEGANS, HOMOLOG OF, A, APH1A 
 
National Institutes of Health

Papers overview

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2017
2017
Gingerol is a major dietary compound that occurs in several plants belonging to the Zingiberaceae family. In the current study… Expand
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Highly Cited
2010
Highly Cited
2010
γ-Secretase is a multiprotein, intramembrane-cleaving protease with a growing list of protein substrates, including the Notch… Expand
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Highly Cited
2009
Highly Cited
2009
Environmental factors are significant contributors for the development of Alzheimer's disease (AD). The greatly increased… Expand
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2009
2009
Gamma-secretase is a unique intramembrane-cleaving protease complex, which cleaves the Alzheimer's disease-associated beta… Expand
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2008
2008
γ-Secretase is an intramembrane cleaving aspartyl protease complex intimately implicated in Alzheimer disease pathogenesis. The… Expand
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Highly Cited
2005
Highly Cited
2005
The role of Notch signaling in general and presenilin in particular was analyzed during mouse somitogenesis. We visualize… Expand
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Highly Cited
2005
Highly Cited
2005
APH-1 (anterior pharynx defective) along with nicastrin and PEN-2 (presenilin enhancer) are essential components of the… Expand
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Highly Cited
2004
Highly Cited
2004
The gamma-secretase complex catalyzes the final intramembraneous cleavage of the beta-amyloid precursor protein, liberating the… Expand
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Highly Cited
2004
Highly Cited
2004
Gamma-secretase is a high molecular weight protein complex composed of four subunits, namely, presenilin (PS; 1 or 2), nicastrin… Expand
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Highly Cited
2003
Highly Cited
2003
APH-1 and PEN-2 genes modulate the function of nicastrin and the presenilins in Caenorhabditis elegans. Preliminary studies in… Expand
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